METHODS A Medline search (1966 to May 2001) was performed to identify all randomized,
clinical trials published in English-language journals, in which a single dose of GC was …

Objectives: The objectives of this review are to discuss the pathophysiology of the pro-
inflammatory response to the cardiopulmonary bypass circuit, the impact of ischemia …

Glucocorticoids continue to be the ma‐jor immunomodulatory agents used in clinical
medicine today. However, their actions as anti‐inflammatory and immunosuppressive drugs …

Cardiopulmonary bypass is known to trigger a global inflammatory response. Age-
dependent differences in the inflammatory response, the increased susceptibility to injury of …

Disclaimer 2020: The EACTS/AEPC Guidelines represent the views of the EACTS and the
AEPC and were produced after careful consideration of the scientific and medical …

Hypothermia is defined as a decrease in body core temperature to below 35° C. In cardiac
surgery, four stages of hypothermia are distinguished: mild, moderate, deep, and profound …

Study objectives Cardiac surgery with cardiopulmonary bypass (CPB) results in
perioperative organ damage caused by the systemic inflammatory response syndrome …

Background There are few detailed descriptions of the inflammatory response to cardiac
surgery with cardiopulmonary bypass (CPB) in children beyond 24 h postoperatively. This is …

Abstract Abstract Objective. Type and frequency of postoperative abnormalities were
registered after cardiovascular surgery to evaluate the aetiology and diagnostic value of …

Background—Steroid administration during cardiopulmonary bypass is thought to improve
cardiopulmonary function by modulating bypass-related inflammation. This study was …