Harnessing genomic information for livestock improvement

M Georges, C Charlier, B Hayes - Nature Reviews Genetics, 2019 - nature.com
The world demand for animal-based food products is anticipated to increase by 70% by
2050. Meeting this demand in a way that has a minimal impact on the environment will …

Role of fatty acids in milk fat and the influence of selected factors on their variability—a review

O Hanuš, E Samková, L Křížová, L Hasoňová, R Kala - Molecules, 2018 - mdpi.com
Fatty acids (FAs) of milk fat are considered to be important nutritional components of the
diets of a significant portion of the human population and substantially affect human health …

[HTML][HTML] Invited review: Milk lactose—Current status and future challenges in dairy cattle

A Costa, N Lopez-Villalobos, NW Sneddon… - Journal of dairy …, 2019 - Elsevier
Lactose is the main carbohydrate in mammals' milk, and it is responsible for the osmotic
equilibrium between blood and alveolar lumen in the mammary gland. It is the major bovine …

Confirmed effects of candidate variants for milk production, udder health, and udder morphology in dairy cattle

T Tribout, P Croiseau, R Lefebvre, A Barbat… - Genetics Selection …, 2020 - Springer
Background Over the last years, genome-wide association studies (GWAS) based on
imputed whole-genome sequences (WGS) have been used to detect quantitative trait loci …

Genetic variation in histone modifications and gene expression identifies regulatory variants in the mammary gland of cattle

CP Prowse-Wilkins, TJ Lopdell, R Xiang… - BMC genomics, 2022 - Springer
Background Causal variants for complex traits, such as eQTL are often found in non-coding
regions of the genome, where they are hypothesised to influence phenotypes by regulating …

A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle

YL Lee, H Takeda, G Costa Monteiro Moreira… - PLoS …, 2021 - journals.plos.org
Clinical mastitis (CM) is an inflammatory disease occurring in the mammary glands of
lactating cows. CM is under genetic control, and a prominent CM resistance QTL located on …

[HTML][HTML] Comparison of the genetic characteristics of directly measured and Fourier-transform mid-infrared-predicted bovine milk fatty acids and proteins

KM Tiplady, TJ Lopdell, RG Sherlock, TJJ Johnson… - Journal of Dairy …, 2022 - Elsevier
Fourier-transform mid-infrared (FT-MIR) spectroscopy is a high-throughput and inexpensive
methodology used to evaluate concentrations of fat and protein in dairy cattle milk samples …

Sequence-based GWAS, network and pathway analyses reveal genes co-associated with milk cheese-making properties and milk composition in Montbéliarde cows

MP Sanchez, Y Ramayo-Caldas, V Wolf… - Genetics Selection …, 2019 - Springer
Background Milk quality in dairy cattle is routinely assessed via analysis of mid-infrared
(MIR) spectra; this approach can also be used to predict the milk's cheese-making properties …

Sequence-based genome-wide association study of individual milk mid-infrared wavenumbers in mixed-breed dairy cattle

KM Tiplady, TJ Lopdell, E Reynolds… - Genetics Selection …, 2021 - Springer
Background Fourier-transform mid-infrared (FT-MIR) spectroscopy provides a high-
throughput and inexpensive method for predicting milk composition and other novel traits …

[HTML][HTML] Genome-wide association study for milk production traits in a Brazilian Holstein population

LHS Iung, J Petrini, J Ramírez-Díaz, M Salvian… - Journal of dairy …, 2019 - Elsevier
Advances in the molecular area of selection have expanded knowledge of the genetic
architecture of complex traits through genome-wide association studies (GWAS). Several …