Known to have affected around 340 million people across the world in 2018, asthma is a
prevalent chronic inflammatory disease of the airways. The symptoms such as wheezing …

Mesenchymal cells in the lung are crucial during development, but also contribute to the
pathogenesis of fibrotic disorders, including idiopathic pulmonary fibrosis (IPF), the most …

Bronchial asthma is a heterogeneous disease characterized by persistent respiratory system
inflammation, airway hyperreactivity, and airflow obstruction. Airway remodeling, defined as …

Introduction Asthma is characterized by enhanced airway contractility and remodeling where
airway smooth muscle (ASM) plays a key role, modulated by inflammation. Understanding …

Smooth muscles are a specific muscle subtype that is widely identified in the tissues of
internal passageways. This muscle subtype has the capacity for controlled or regulated …

Asthma is a chronic inflammatory disease that has been associated with insufficient
vegetable intake. Allyl Isothiocyanate (AITC) is a natural isothiocyanate found in cruciferous …

Transient receptor potential (TRP) ion channels play critical roles in physiological and
pathological conditions. Increasing evidence has unveiled the contribution of TRP vanilloid …

In this study, we confirmed that thrombin significantly increases the production of COX-2 and
PGE2 in human tracheal smooth muscle cells (HTSMCs), leading to inflammation in the …

Introduction. Androgen signaling comprises nongenomic and genomic pathways.
Nongenomic actions are not related to the binding of the androgen receptor (AR) and occur …

Diseases such as asthma are exacerbated by inflammation, cigarette smoke and even
nicotine delivery devices such as e-cigarettes. However, there is currently little information …