Reversible male contraception by targeted inhibition of serine/threonine kinase 33
Men or mice with homozygous serine/threonine kinase 33 (STK33) mutations are sterile
owing to defective sperm morphology and motility. To chemically evaluate STK33 for male …
owing to defective sperm morphology and motility. To chemically evaluate STK33 for male …
Structural comparison of substrate-binding pockets of serine β-lactamases in classes A, C, and D
H Lee, H Park, K Kwak, C Lee, J Yun… - Journal of Enzyme …, 2025 - Taylor & Francis
Abstract β-lactams have been the most successful antibiotics, but the rise of multi-drug
resistant (MDR) bacteria threatens their effectiveness. Serine β-lactamases (SBLs), among …
resistant (MDR) bacteria threatens their effectiveness. Serine β-lactamases (SBLs), among …
Discovery of highly potent and ALK2/ALK1 selective kinase inhibitors using DNA-encoded chemistry technology
Activin receptor type 1 (ACVR1; ALK2) and activin receptor like type 1 (ACVRL1; ALK1) are
transforming growth factor beta family receptors that integrate extracellular signals of bone …
transforming growth factor beta family receptors that integrate extracellular signals of bone …