Formation and repair of oxidatively generated damage in cellular DNA

J Cadet, KJA Davies, MHG Medeiros… - Free Radical Biology …, 2017 - Elsevier
In this review article, emphasis is placed on the critical survey of available data concerning
modified nucleobase and 2-deoxyribose products that have been identified in cellular DNA …

Recent advances and perspectives of molecularly imprinted polymer-based fluorescent sensors in food and environment analysis

G Liu, X Huang, L Li, X Xu, Y Zhang, J Lv, D Xu - Nanomaterials, 2019 - mdpi.com
Molecular imprinting technology (MIT), also known as molecular template technology, is a
new technology involving material chemistry, polymer chemistry, biochemistry, and other …

Advances in sample extraction

S Tang, H Zhang, HK Lee - Analytical chemistry, 2016 - ACS Publications
Analyte or sample extraction is the most basic, yet a very important and dominant, feature of
any sample preparation technique which in general can also include other processes such …

[HTML][HTML] Association between oxidative DNA damage and risk of colorectal cancer: sensitive determination of urinary 8-hydroxy-2′-deoxyguanosine by UPLC-MS/MS …

C Guo, X Li, R Wang, J Yu, M Ye, L Mao, S Zhang… - Scientific reports, 2016 - nature.com
Oxidative DNA damage plays crucial roles in the pathogenesis of numerous diseases
including cancer. 8-hydroxy-2′-deoxyguanosine (8-OHdG) is the most representative …

Bisulfite-free and single-nucleotide resolution sequencing of DNA epigenetic modification of 5-hydroxymethylcytosine using engineered deaminase

NB Xie, M Wang, TT Ji, X Guo, JH Ding, BF Yuan… - Chemical …, 2022 - pubs.rsc.org
The discovery of 5-hydroxymethylcytosine (5hmC) in mammalian genomes is a landmark in
epigenomics study. Similar to 5-methylcytosine (5mC), 5hmC is viewed as a critical …

Transformation of 5-carboxylcytosine to cytosine through C–C bond cleavage in human cells constitutes a novel pathway for DNA demethylation

Y Feng, NB Xie, WB Tao, JH Ding, XJ You… - CCS …, 2021 - chinesechemsoc.org
Active demethylation of 5-methylcytosine (5mC) can be realized through ten-eleven
translocation (TET) dioxygenase-mediated oxidation of 5mC to 5-hydroxymethylcytosine …

The existence of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA and RNA in mammals

HY Zhang, J Xiong, BL Qi, YQ Feng… - Chemical …, 2016 - pubs.rsc.org
We developed a novel strategy by oxidation–derivatization combined mass spectrometry
analysis for the determination of 5-hydroxymethylcytosine and 5-formylcytosine in both DNA …

AlkB Homologue 1 Demethylates N3-Methylcytidine in mRNA of Mammals

CJ Ma, JH Ding, TT Ye, BF Yuan… - ACS chemical biology, 2019 - ACS Publications
RNA contains diverse modifications that exert important influences in a variety of cellular
processes. So far more than 150 modifications have been identified in various RNA species …

Photoelectrochemical biosensor for DNA hydroxymethylation detection based on the enhanced photoactivity of in-situ synthesized Bi4NbO8Cl@ Bi2S3 heterojunction

J Ding, Y Zhou, Q Wang, S Ai - Biosensors and Bioelectronics, 2021 - Elsevier
As an important epigenetic modification, 5-hydroxymethylcytosine (5hmC) aroused wide
concern about the distribution and the function. Due to the necessity of 5hmC detection, a …

Chemical tagging for sensitive determination of uridine modifications in RNA

QY Cheng, J Xiong, CJ Ma, Y Dai, JH Ding, FL Liu… - Chemical …, 2020 - pubs.rsc.org
The discovery of dynamic and reversible modifications in messenger RNA (mRNA) is
opening new directions in RNA modification-mediated regulation of biological processes …