Considerations for the development of monoclonal antibodies to address new viral variants in COVID-19

A Casadevall, S McConnell… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Monoclonal antibody (mAb) therapies proved safe and effective in preventing
progression of COVID-19 to hospitalization, but most were eventually defeated by continued …

The impact of treatment strategies on the epidemiological dynamics of plasmid-conferred antibiotic resistance

M Muetter, DC Angst, RR Regoes… - Proceedings of the …, 2024 - pnas.org
The issue of antibiotic resistance is a critical concern for public health, prompting numerous
investigations into the impact of treatment strategies on preventing or slowing down the …

The many dimensions of combination therapy: How to combine antibiotics to limit resistance evolution

C Nyhoegen, S Bonhoeffer… - Evolutionary …, 2024 - Wiley Online Library
In combination therapy, bacteria are challenged with two or more antibiotics simultaneously.
Ideally, separate mutations are required to adapt to each of them, which is a priori expected …

The antibacterial and anti-biofilm effects of novel synthetized nitroimidazole compounds against methicillin-resistant Staphylococcus aureus and carbapenem …

E Zarenezhad, E Behmard, R Karami, S Behrouz… - BMC chemistry, 2024 - Springer
The antibiotic resistance and biofilm formation by bacterial pathogens has led to failure in
infections elimination. This study aimed to assess the antibacterial and anti-biofilm …

The antimicrobial and antibiofilm effects of gentamicin, imipenem, and fucoidan combinations against dual-species biofilms of Staphylococcus aureus and …

M Nazari, M Taheri, F Nouri, M Bahmanzadeh… - Annals of Clinical …, 2024 - Springer
Introduction Diabetes mellitus is a chronic metabolic disorder characterized by persistent
hyperglycemia due to impaired insulin production or utilization, leading to severe health …