TGF-β1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistence

C Sun, B Fu, Y Gao, X Liao, R Sun, Z Tian… - PLoS …, 2012 - journals.plos.org
The mechanism underlying persistent hepatitis B virus (HBV) infection remains unclear. We
investigated the role of innate immune responses to persistent HBV infection in 154 HBV …

A meta‐analysis comparing the efficacy of entecavir and tenofovir for the treatment of chronic hepatitis B infection

SR Zuo, XC Zuo, CJ Wang, YT Ma… - The Journal of …, 2015 - Wiley Online Library
The efficacy of entecavir and tenofovir in patients with chronic hepatitis B virus (HBV) is
inconsistent. To address this issue, we conducted a meta‐analysis based on a current …

Incidence of natural resistance mutations in naïve chronic hepatitis B patients: A systematic review and meta‐analysis

Q Zhang, Y Liao, B Cai, Y Li, L Li… - Journal of …, 2015 - Wiley Online Library
Abstract Background and Aim Studies focused on the naturally occurring resistance
mutation rate in treatment‐naïve chronic hepatitis B (CHB) patients have set off a furious …

Efficacy of tenofovir in preventing perinatal transmission of HBV infection in pregnant women with high viral loads

Y Lin, Y Liu, G Ding, L Touqui, W Wang, N Xu, K Liu… - Scientific reports, 2018 - nature.com
Mother-to-child transmission is the major cause of chronic hepatitis B virus (HBV) infection.
This double-blind trial tested the effect of tenofovir disoproxil fumarate (TDF) in preventing …

A novel nomogram to predict evident histological liver injury in patients with HBeAg-positive chronic hepatitis B virus infection

X Chang, J Wang, Y Chen, Q Long, L Song, Q Li… - …, 2021 - thelancet.com
Background HBeAg-positive chronic infection is a unique phase of chronic hepatitis B virus
(HBV) infection. Current guidelines advise against starting antiviral treatment for HBeAg …

Prevalence of hepatitis B virus infection in Shenzhen, China, 2015–2018

J Tao, W Zhang, H Yue, G Zhu, W Wu, W Gong… - Scientific reports, 2019 - nature.com
China has nearly 10% of the general HBV carrier population in the world; this infection is the
most common cause of chronic liver disease. Understanding HBV epidemiology is essential …

Epidemiology study of HBV genotypes and antiviral drug resistance in multi-ethnic regions from Western China

Q Zhang, Y Liao, J Chen, B Cai, Z Su, B Ying, X Lu… - Scientific reports, 2015 - nature.com
Hepatitis B virus (HBV) infection is a critical global health issue and moderately epidemic in
Western China, but HBV molecular epidemiology characteristics are still limited. We …

Potential resistant mutations within HBV reverse transcriptase sequences in nucleos (t) ide analogues-experienced patients with hepatitis B virus infection

X Zhang, X Chen, M Wei, C Zhang, T Xu, L Liu, Z Xu - Scientific reports, 2019 - nature.com
This study was performed to analyze the potential resistant mutations within HBV reverse
transcriptase (RT) sequences against nucleos (t) ide analogues (NA). HBV DNA RT region …

Quantitation of HBV covalently closed circular DNA in micro formalin fixed paraffin-embedded liver tissue using rolling circle amplification in combination with real-time …

Y Zhong, J Han, Z Zou, S Liu, B Tang, X Ren, X Li… - Clinica chimica acta, 2011 - Elsevier
Background The study aimed to develop an effective method to quantitate HBV covalently
closed circular DNA (cccDNA) using small section of formalin fixed paraffin-embedded …

[HTML][HTML] Avasimibe inhibits the proliferation, migration and invasion of glioma cells by suppressing linc00339

Y Luo, L Liu, X Li, Y Shi - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Glioma is one of the most destructive human tumours. Although standard treatment has
improved the prognosis for glioma patients, the survival of glioma patients is still …