Switching between anti-VEGF agents in the management of refractory diabetic macular edema: A systematic review

K Madjedi, A Pereira, BG Ballios, P Arjmand… - Survey of …, 2022 - Elsevier
Refractory diabetic macular edema (DME) to monthly intravitreal anti-vascular endothelial
growth factor (VEGF) monotherapy has a prevalence of approximately 40% in landmark …

Review of clinical studies and recommendation for a therapeutic flow chart for diabetic macular edema

S Yoshida, T Murakami, M Nozaki, K Suzuma… - Graefe's Archive for …, 2021 - Springer
Diabetic macular edema (DME), characterized by exudative fluid accumulation in the
macula, is the most common form of sight-threatening retinopathy in patients with diabetes …

[HTML][HTML] Efficacy of switching therapy to aflibercept for patients with persistent diabetic macular edema: a systematic review and meta-analysis

Y Liu, J Cheng, Y Gao, L Qin, X Min… - Annals of translational …, 2020 - ncbi.nlm.nih.gov
Background To evaluate functional and anatomical consequences of switching anti-vascular
endothelial growth factor (anti-VEGF) therapy from bevacizumab and/or ranibizumab to …

Modified early intensive and treat-and-extend regimen of anti-vascular endothelial growth factor for diabetic macular edema in Taiwan

JF Chou, JS Wu, YL Chen, SN Chen - Scientific Reports, 2023 - nature.com
Given the rising prevalence of patients with diabetes and increasing treatment burden for
patients with vision-threatening diabetic macular edema (DME), we aimed to explore the …

Switching to Conbercept in Diabetic Macular Edema After Unsatisfactory Response to Previous Intravitreal Injection of Ranibizumab

P Xing, B Meng, X Hu, W Qu, S Wang - Clinical Ophthalmology, 2023 - Taylor & Francis
Objective To assess the functional and anatomical effects of transitioning to conbercept
intravitreal injection (IVC) treatment in patients with diabetic macular edema (DME) who had …

Anti-VEGF agents in the management of diabetic macular edema

AS Li, M Veerappan, V Mittal, DV Do - Expert Review of …, 2020 - Taylor & Francis
Introduction Diabetic macular edema (DME) is a common cause of vision loss in patients
with diabetic retinopathy and occurs in a substantial proportion of patients with long …

Safety and Outcomes of Intravitreal Aflibercept in Diabetic Macular Edema–A Systematic Review

AM Dascalu, M Rizzo, AA Rizvi… - Current …, 2022 - ingentaconnect.com
Background: Recent evidence on the role of vascular endothelial growth factor (VEGF) in the
pathogenesis of ischemia and microvascular hyperpermeability leading to macular edema …

Changes in metamorphopsia following intravitreal aflibercept injection for diabetic macular edema

T Murakami, F Okamoto, Y Sugiura, S Morikawa… - Scientific Reports, 2022 - nature.com
The aim of the present study was to investigate changes in metamorphopsia in patients with
diabetic macular edema (DME) following intravitreal aflibercept injection (IVA) with the treat …

[HTML][HTML] PF4 antagonizes retinal neovascularization via inhibiting PRAS40 phosphorylation in a mouse model of oxygen-induced retinopathy

S Cai, Q Yang, Y Cao, Y Li, J Liu, J Wang… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Retinal neovascularization (RNV) is a common pathology of blinding proliferative
retinopathies. The current treatments to RNV, however, are hindered by limited efficacy, side …