State-of-the-art colorectal disease: postoperative ileus

NP Sommer, R Schneider, S Wehner, JC Kalff… - International journal of …, 2021 - Springer
Abstract Purpose Postoperative Ileus (POI) remains an important complication for patients
after abdominal surgery with an incidence of 10–27% representing an everyday issue for …

Gastroparesis

M Camilleri, KM Sanders - Gastroenterology, 2022 - Elsevier
Gastroparesis is characterized by symptoms suggestive of, and objective evidence of,
delayed gastric emptying in the absence of mechanical obstruction. This review addresses …

Electroacupuncture vs sham electroacupuncture in the treatment of postoperative ileus after laparoscopic surgery for colorectal cancer: a multicenter, randomized …

Y Wang, JW Yang, SY Yan, Y Lu, JG Han, W Pei… - JAMA …, 2023 - jamanetwork.com
Importance Despite the adoption of the optimized Enhanced Recovery After Surgery (ERAS)
protocol, postoperative ileus (POI) severely impairs recovery after colorectal resection and …

IL-1-dependent enteric gliosis guides intestinal inflammation and dysmotility and modulates macrophage function

R Schneider, P Leven, S Mallesh, M Breßer… - Communications …, 2022 - nature.com
Abstract Muscularis Externa Macrophages (ME-Macs) and enteric glial cells (EGCs) are
closely associated cell types in the bowel wall, and important interactions are thought to …

Opioid-free versus opioid-based anesthesia in pancreatic surgery

S Hublet, M Galland, J Navez, P Loi, J Closset… - BMC …, 2022 - Springer
Background Opioid-free anesthesia (OFA) is associated with significantly reduced
cumulative postoperative morphine consumption in comparison with opioid-based …

β-adrenergic signaling triggers enteric glial reactivity and acute enteric gliosis during surgery

P Leven, R Schneider, L Schneider, S Mallesh… - Journal of …, 2023 - Springer
Background Enteric glia contribute to the pathophysiology of various intestinal immune-
driven diseases, such as postoperative ileus (POI), a motility disorder and common …

General anesthesia bullies the gut: a toxic relationship with dysbiosis and cognitive dysfunction

L Liu, L Shang, D Jin, X Wu, B Long - Psychopharmacology, 2022 - Springer
Perioperative neurocognitive disorder (PND) is a common surgery outcome affecting up to a
third of the elderly patients, and it is associated with high morbidity and increased risk for …

[HTML][HTML] Comparison of postoperative nausea and vomiting between remimazolam and propofol: a propensity score-matched, retrospective, observational, single …

Y Suzuki, S Kawashima, H Makino… - Korean Journal of …, 2023 - synapse.koreamed.org
Background Remimazolam is a novel ultrashort-acting benzodiazepine that has recently
become available for general anesthesia. However, the incidence of postoperative nausea …

A randomised pilot trial of virtual reality-based relaxation for enhancement of perioperative well-being, mood and quality of life

MC Schrempf, J Petzold, MA Petersen, TT Arndt… - Scientific Reports, 2022 - nature.com
A cancer diagnosis and subsequent treatment can trigger distress, negatively impact coping
resources, and affect well-being as well as quality of life. The aim of this pilot study was to …

[HTML][HTML] Role of macrophages and mast cells as key players in the maintenance of gastrointestinal smooth muscle homeostasis and disease

M Mischopoulou, M D'Ambrosio, E Bigagli… - Cellular and Molecular …, 2022 - Elsevier
The gut contains the largest macrophage pool in the body, with populations of macrophages
residing in the mucosa and muscularis propria of the gastrointestinal (GI) tract. Muscularis …