Rodent models of AKI and AKI-CKD transition: an update in 2024

Y Fu, Y Xiang, Q Wei… - American Journal of …, 2024 - journals.physiology.org
Despite known drawbacks, rodent models are essential tools in the research of renal
development, physiology, and pathogenesis. In the past decade, rodent models have been …

The application strategy of liposomes in organ targeting therapy

Z Xun, T Li, X Xue - Wiley Interdisciplinary Reviews …, 2024 - Wiley Online Library
Liposomes—microscopic phospholipid bubbles with bilayered membrane structure—have
been a focal point in drug delivery research for the past 30 years. Current liposomes …

Activation of angiotensin II type 2 receptor leads to preservation of primary cilia in tubular cells during renal ischaemia‐reperfusion injury

TR Maknis, MF Fussi, AP Pariani, V Huhn… - The Journal of …, 2024 - Wiley Online Library
Abstract Ischaemia‐reperfusion (IR)‐associated acute kidney injury (AKI) is a severe clinical
condition that lacks effective pharmacological treatments. Our recent research revealed that …

Beneficial effects of selenium on kidney injury via Nf-Kb and Aquaporin-1 levels

B Candan, NF Karakuyu, K Gülle, E Sarman… - … Trace Element Research, 2024 - Springer
Systemic inflammation is a serious condition that can affect various tissues and organs, such
as the kidneys, and can be life-threatening. Selenium (Se) is an antioxidant and anti …

Angiotensin II Type 2 Receptor Inhibits M1 Polarization and Apoptosis of Alveolar Macrophage and Protects Against Mechanical Ventilation-Induced Lung Injury

X Zheng, Z Xu, L Xu, L Wang, S Qin, L Ying, S Dong… - Inflammation, 2024 - Springer
Abstract Angiotensin II (Ang II) is associated with macrophage polarization and apoptosis,
but the role of the angiotensin type 2 receptor (AT2R) in these processes remains …

[HTML][HTML] Irbesartan restored aquaporin-1 levels via inhibition of NF-kB expression in acute kidney injury model

B Candan, I Ilhan, E Sarman, M Sevimli - Nefrología (English Edition), 2024 - Elsevier
Introduction Acute kidney injury (AKI) is a serious pathology that progress with dysfunction of
regulating blood pressure and fluid balance, concentrating urine due to decrement of …

[PDF][PDF] Angiotensin II Type 2 Receptor Antibodies in Glomerular Diseases

M Szymczak, H Heidecke, M Żabińska… - Archivum …, 2024 - sciendo.com
We evaluated the concentration of AT2R antibodies in 136 patients with primary and
secondary glomerular diseases: membranous nephropathy (n= 18), focal and segmental …