Objective: The international SWEET registry (NCT04427189) was initiated in 2008 to
improve outcomes in pediatric diabetes. A 10-year follow-up allowed studying time trends of …

Cardiovascular disease (CVD) is a major cause of mortality in type 1 diabetes mellitus
(T1D). However, evidence of its risks and management is often extrapolated from studies in …

Cardiovascular disease (CVD) is the primary cause of higher and earlier morbidity and
mortality in people with type 1 diabetes (T1D) compared to people without diabetes. In …

The cause of T1DM is the subject of multiple ongoing studies with the shared goal of
identifying targets for prevention. 10, 11 A cure is likely still far in the future, barring dramatic …

Background: Dyslipidemia increases the frequency and severity of micro and macrovascular
complications of type 1 diabetes (T1D). The present study aims to determine the prevalence …

1-Deoxysphingolipids (1-deoxySLs) are atypical neurotoxic sphingolipids that are formed by
the serine-palmitoyltransferase (SPT). Pathologically elevated 1-deoxySL concentrations …

OBJECTIVE: To test the hypothesis that a change in glycated hemoglobin (A1c) over a
follow-up interval of approximately 2 years would be associated with concomitant changes …

OBJECTIVE Understanding the risk factors associated with progression and regression of
dyslipidemia in youth with type 1 diabetes may guide treatments. RESEARCH DESIGN AND …

Objective: Cardiovascular diseases (CVD) are the most important cause of morbidity and
mortality in patients with type 1 diabetes (T1D). Children with T1D have a similar or higher …

OBJECTIVE Youth with type 1 diabetes have worse cardiovascular (CV) risk factors and
higher carotid intima-media thickness (IMT) than their peers without diabetes. Whether the …