The human gastrointestinal tract is colonized by trillions of microorganisms that interact with
the host to maintain structural and functional homeostasis. Acting as the interface between …

Abstract The Suppression of Tumorigenicity 2 protein (ST2) is a member of the interleukin
(IL) 1 receptor family with transmembrane (ST2L) and soluble (sST2) isoforms that are (over) …

The intestinal immune system maintains a delicate balance between immunogenicity
against invading pathogens and tolerance of the commensal microbiota. Inflammatory bowel …

The gut microbiota plays a key role in host health and disease, particularly through their
interactions with the immune system. Intestinal homeostasis is dependent on the symbiotic …

Inflammatory bowel disease (IBD) is a chronic recurrent inflammatory disease of the
intestine, including Crohn's disease (CD) and ulcerative colitis (UC), whose etiology and …

The intestinal tract is densely populated by microbiota consisting of various commensal
microorganisms that are instrumental for the healthy state of the living organism. Such …

Inflammatory bowel disease (IBD), consisting of ulcerative colitis (UC) and Crohn's disease
(CD), is featured by overactive immune response and enduring course of unrestrained …

Background Octopus vulgaris is a highly valuable species of great commercial interest and
excellent candidate for aquaculture diversification; however, the octopus' well-being is …

Abstract Background and Aims: Proper interpretation of data from preclinical animal studies
requires thorough knowledge of the pathophysiology of both the human disease and animal …

The ability to distinguish pathogens from self-antigens is one of the most important functions
of the immune system. However, this simple self versus non-self assignment belies the …