[HTML][HTML] Emerging Biomarkers in Metabolomics: Advancements in Precision Health and Disease Diagnosis

DK Vo, KTL Trinh - International Journal of Molecular Sciences, 2024 - mdpi.com
Metabolomics has come to the fore as an efficient tool in the search for biomarkers that are
critical for precision health approaches and improved diagnostics. This review will outline …

[HTML][HTML] Non-canonical pathways associated to Amyloid beta and tau protein dyshomeostasis in Alzheimer's disease: A narrative review

A Maggiore, V Latina, M D'Erme, G Amadoro… - Ageing Research …, 2024 - Elsevier
Alzheimer's Disease (AD) is the most common form of dementia among elderly people. This
disease imposes a significant burden on the healthcare system, society, and economy due …

[HTML][HTML] Role of dietary and nutritional interventions in ceramide-associated diseases

S Wang, Z Jin, B Wu, AJ Morris, P Deng - Journal of Lipid Research, 2024 - Elsevier
Ceramides are important intermediates in sphingolipid metabolism and serve as signaling
molecules with independent biological significance. Elevated cellular and circulating …

The early diagnosis of Alzheimer's disease: Blood‐based panel biomarker discovery by proteomics and metabolomics

Y Dong, X Song, X Wang, S Wang… - CNS Neuroscience & …, 2024 - Wiley Online Library
Diagnosis and prediction of Alzheimer's disease (AD) are increasingly pressing in the early
stage of the disease because the biomarker‐targeted therapies may be most effective …

Basic, Translational, and Clinical Research on Dementia

G Bagetta, D Bano, D Scuteri - International Journal of Molecular …, 2024 - mdpi.com
The global impact of dementia is an increasing area of concern and, according to the
Alzheimer's Disease International (ADI) World Alzheimer Report 2021, up to 90% of …

[HTML][HTML] Enhancing Biomedicine: Proteomics and Metabolomics in Action

M Costanzo, M Caterino, L Santorelli - Proteomes, 2025 - mdpi.com
The rapid and substantial advancements in proteomic and metabolomic technologies have
revolutionized our ability to investigate biological systems. These modern techniques have …

A review of the mechanisms of abnormal ceramide metabolism in type 2 diabetes mellitus, Alzheimer's disease, and their co-morbidities

Y Pan, J Li, P Lin, L Wan, Y Qu, L Cao… - Frontiers in …, 2024 - frontiersin.org
The global prevalence of type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD) is
rapidly increasing, revealing a strong association between these two diseases. Currently …

Clinical advances in analytical profiling of signature lipids: implications for severe non-communicable and neurodegenerative diseases

S Sarkar, D Roy, B Chatterjee, R Ghosh - Metabolomics, 2024 - Springer
Background Lipids play key roles in numerous biological processes, including energy
storage, cell membrane structure, signaling, immune responses, and homeostasis, making …