Representational drift in the mouse visual cortex

D Deitch, A Rubin, Y Ziv - Current biology, 2021 - cell.com
Recent studies have shown that neuronal representations gradually change over time
despite no changes in the stimulus, environment, or behavior. However, such …

A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging

P Rupprecht, S Carta, A Hoffmann, M Echizen… - Nature …, 2021 - nature.com
Inference of action potentials ('spikes') from neuronal calcium signals is complicated by the
scarcity of simultaneous measurements of action potentials and calcium signals ('ground …

The Neurodata Without Borders ecosystem for neurophysiological data science

O Rübel, A Tritt, R Ly, BK Dichter, S Ghosh, L Niu… - Elife, 2022 - elifesciences.org
The neurophysiology of cells and tissues are monitored electrophysiologically and optically
in diverse experiments and species, ranging from flies to humans. Understanding the brain …

VIP interneurons in mouse primary visual cortex selectively enhance responses to weak but specific stimuli

DJ Millman, GK Ocker, S Caldejon, I Kato, JD Larkin… - Elife, 2020 - elifesciences.org
Vasoactive intestinal peptide-expressing (VIP) interneurons in the cortex regulate feedback
inhibition of pyramidal neurons through suppression of somatostatin-expressing (SST) …

Scaling of sensory information in large neural populations shows signatures of information-limiting correlations

MM Kafashan, AW Jaffe, SN Chettih, R Nogueira… - Nature …, 2021 - nature.com
How is information distributed across large neuronal populations within a given brain area?
Information may be distributed roughly evenly across neuronal populations, so that total …

Reconciling functional differences in populations of neurons recorded with two-photon imaging and electrophysiology

JH Siegle, P Ledochowitsch, X Jia, DJ Millman… - Elife, 2021 - elifesciences.org
Extracellular electrophysiology and two-photon calcium imaging are widely used methods
for measuring physiological activity with single-cell resolution across large populations of …

Transcriptomic cell type structures in vivo neuronal activity across multiple timescales

A Schneider, M Azabou, L McDougall-Vigier, DF Parks… - Cell reports, 2023 - cell.com
Cell type is hypothesized to be a key determinant of a neuron's role within a circuit. Here, we
examine whether a neuron's transcriptomic type influences the timing of its activity. We …

Inferring spikes from calcium imaging in dopamine neurons

W Fleming, S Jewell, B Engelhard, DM Witten… - PloS one, 2021 - journals.plos.org
Calcium imaging has led to discoveries about neural correlates of behavior in subcortical
neurons, including dopamine (DA) neurons. However, spike inference methods have not …

A manifold neural population code for space in hippocampal coactivity dynamics independent of place fields

ERJ Levy, S Carrillo-Segura, EH Park, WT Redman… - Cell reports, 2023 - cell.com
Hippocampus place cell discharge is temporally unreliable across seconds and days, and
place fields are multimodal, suggesting an" ensemble cofiring" spatial coding hypothesis …

Bias-free estimation of information content in temporally sparse neuronal activity

L Sheintuch, A Rubin, Y Ziv - PLoS computational biology, 2022 - journals.plos.org
Applying information theoretic measures to neuronal activity data enables the quantification
of neuronal encoding quality. However, when the sample size is limited, a naïve estimation …