Macrophages are the most abundant immune cells within the synovial joints, and also the
main innate immune effector cells triggering the initial inflammatory responses in the …

Pluripotent stem cells (PSCs) isolated in vitro from embryonic stem cells (ESCs), induced
PSC (iPSC) and also post-implantation epiblast-derived stem cells (EpiSCs) are known for …

Triple-negative breast cancer (TNBC) is cancer that tested as negative for estrogen
receptors (ER), progesterone receptors (PR), and excess human epidermal growth factor …

Many genes and molecules that drive tissue patterning during organogenesis and tissue
regeneration have been discovered. Yet, we still lack a full understanding of how these …

The function of metabolic state in stemness is poorly understood. Mouse embryonicstem
cells (ESC) and epiblast stem cells (EpiSC) are at distinct pluripotent statesrepresenting the …

Cortical development depends on the active integration of cell-autonomous and extrinsic
cues, but the coordination of these processes is poorly understood. Here, we show that the …

Little is known about how the immune system impacts human colorectal cancer
invasiveness and stemness. Here we detected interleukin-22 (IL-22) in patient colorectal …

Cancers may arise from rare self-renewing tumor-initiating cells (T-IC). However, how T-IC
self renewal, multipotent differentiation, and tumorigenicity are maintained remains obscure …

Morphogenesis is the remarkable process by which cells self-assemble into complex tissues
and organs that exhibit specialized form and function during embryological development …

Reprogramming of somatic cells to a pluripotent embryonic stem cell-like state has been
achieved by nuclear transplantation of a somatic nucleus into an enucleated egg and most …