[HTML][HTML] An overview of bioinformatics tools for epitope prediction: implications on vaccine development

RE Soria-Guerra, R Nieto-Gomez… - Journal of biomedical …, 2015 - Elsevier
Exploitation of recombinant DNA and sequencing technologies has led to a new concept in
vaccination in which isolated epitopes, capable of stimulating a specific immune response …

Active immunotherapy: current state of the art in vaccine approaches for NHL

ML Palomba - Current oncology reports, 2012 - Springer
Immune therapy of cancer is a rapidly evolving field, with long-deserved successes now
finally achieved. As new pathways triggered by the immune synapsis are elucidated, and …

[HTML][HTML] B-cell epitope mapping for the design of vaccines and effective diagnostics

TA Ahmad, AE Eweida, SA Sheweita - Trials in Vaccinology, 2016 - Elsevier
The increasing resistance of many microbial strains to antibiotics, delayed laboratory results,
and side effects of many chemotherapeutics has raised the need to search for sensitive …

Vaccinomic approach for novel multi epitopes vaccine against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)

YA Almofti, KA Abd-Elrahman, EEM Eltilib - BMC immunology, 2021 - Springer
Background The spread of a novel coronavirus termed severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) in China and other countries is of great concern worldwide …

Immunoinformatics: a brief review

N Tomar, RK De - Immunoinformatics, 2014 - Springer
A large volume of data relevant to immunology research has accumulated due to
sequencing of genomes of the human and other model organisms. At the same time, huge …

Immunoinformatics approach for multiepitope vaccine prediction from H, M, F, and N proteins of Peste des Petits ruminants virus

BBM Gaafar, SA Ali, KA Abd-Elrahman… - Journal of …, 2019 - Wiley Online Library
Background. Small ruminant morbillivirus or peste des petits ruminants virus (PPRV) is an
acute and highly contagious viral disease of goats, sheep, and other livestock. This study …

Lymphoma immunotherapy: current status

R Zappasodi, F De Braud, M Di Nicola - Frontiers in Immunology, 2015 - frontiersin.org
The rationale to treat lymphomas with immunotherapy comes from long-standing evidence
on their distinctive immune responsiveness. Indolent B-cell non-Hodgkin lymphomas, in …

In silico analyses of Wilms׳ tumor protein to designing a novel multi-epitope DNA vaccine against cancer

S Khalili, MR Rahbar, MH Dezfulian… - Journal of theoretical …, 2015 - Elsevier
Predefined and pre-weighted objective criteria and essential role of Wilms׳ tumor wild type
gene (WT1) for maintaining transformed features of cancer cells confirm the high potency of …

Immunogenicity Evaluation of a Rationally Designed Polytope Construct Encoding HLA-A*0201 Restricted Epitopes Derived from Leishmania major Related Proteins …

N Seyed, T Taheri, C Vauchy, M Dosset, Y Godet… - PLoS …, 2014 - journals.plos.org
Background There are several reports demonstrating the role of CD8 T cells against
Leishmania species. Therefore peptide vaccine might represent an effective approach to …

Novel approaches in polyepitope T-cell vaccine development against HIV-1

LI Karpenko, SI Bazhan, DV Antonets… - Expert review of …, 2014 - Taylor & Francis
RV144 clinical trial was modestly effective in preventing HIV infection. New alternative
approaches are needed to design improved HIV-1 vaccines and their delivery strategies …