Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary
metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum …

Low back pain (LBP) is a major reason for disability, and symptomatic intervertebral disc
(IVD) degeneration (IDD) contributes to roughly 40% of all LBP cases. Current treatment …

The importance of gut microbiota in human health and pathophysiology is undisputable.
Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in …

Urolithins are dibenzo [b, d] pyran‐6‐one derivatives that are produced by the human gut
microbiota from ellagitannins and ellagic acid (EA). These metabolites are much better …

There is substantial interest in the role of plant secondary metabolites as protective dietary
agents. In particular, the involvement of flavonoids and related compounds has become a …

The risk of developing pregnancy-induced hypertension and preeclampsia is higher in
obese pregnant women. In obesity, the composition of the gut microbiota is altered. Obesity …

The Keap1/Nrf2/ARE system is a central defensive mechanism against oxidative stress
which plays a key role in the pathogenesis and progression of many diseases. Nrf2 is a …

Foods rich in ellagic tannins are first hydrolyzed into ellagic acid in the stomach and small
intestine, and then converted into urolithins with high bioavailability by the intestinal flora …

The health benefits attributed to pomegranate have been associated with its high content in
polyphenols, particularly ellagitannins. This is also the case for other ellagitannin‐containing …

Background Alzheimer's disease (AD) is a progressive neurodegenerative disorder
characterized by an abnormal accumulation of amyloid-β (Aβ) plaques, neuroinflammation …