Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …

Yersinia enterocolitica is the causative agent of yersiniosis, a zoonotic disease of growing
epidemiological importance with significant consequences for public health. This pathogenic …

The type III secretion system (T3SS) is a virulence apparatus used by many Gram-negative
pathogenic bacteria to cause infections. Pathogens utilizing a T3SS are responsible for …

Infections caused by Gram-negative pathogens pose a major health burden. Both
respiratory and gastrointestinal infections are commonly associated with these pathogens …

Antibiotic resistance is a great and growing threat to public health, motivating scientists to
find innovative strategies to cure infections (1‐3). An alternative approach toclassical …

Extensively produced by members of the genus Streptomyces, piericidins are a large family
of microbial metabolites, which consist of main skeleton of 4‐pyridinol with methylated …

The uncontrollable spread of superbugs calls for new approaches in dealing with microbial-
antibiotic resistance. Accordingly, the anti-virulence approach has arisen as an attractive …

Many known inhibitors of the bacterial type III secretion system (T3SS), a virulence factor
used by pathogenic bacteria to infect host cells, are natural products. These compounds …

The type III secretion system (T3SS) is a key virulence determinant in the infection process of
Pseudomonas syringae pv. tomato DC3000 (Pst DC3000). Pathogen constructs a type III …

Pectobacterium atrosepticum (P. atrosepticum: Pba) which causes potato soft rot and
blackleg is a notorious plant pathogen worldwide. Discovery of new types of antimicrobial …