Autoimmune diseases (AIDs) are the consequence of a breach in immune tolerance,
leading to the inability to sufficiently differentiate between self and non-self. Immune …

Age-associated B cells (ABCs) are a transcriptionally and functionally unique B cell
population. In addition to arising with age and following infection, ABCs are expanded …

Age-associated B cells (ABCs) are a recently identified, unique B cell population that
displays both protective and pathogenic characteristics, depending on the context. A major …

B cells expressing the transcription factor T-bet are found to have a protective role in viral
infections, but are also considered major players in the onset of different types of …

Human B cells encompass functionally diverse lineages and phenotypic states that
contribute to protective as well as pathogenic responses. Epstein-Barr virus (EBV) provides …

The understanding of immune dysregulation in many different diseases continues to grow.
There is increasing evidence that altered microbiome and gut barrier dysfunction contribute …

Age/autoimmunity-associated B cells (ABCs) are a novel B cell subpopulation with a unique
transcriptional signature and cell surface phenotype. They are not sensitive to BCR but rely …

Abstract Epstein-Barr Virus (EBV), a dsDNA herpesvirus, is believed to play a significant role
in exacerbating and potentially triggering autoimmune and autoinflammatory maladies …

Introduction The serological biomarker anti-citrullinated protein antibodies (ACPAs) may
have several functions but is especially important for the diagnosis of rheumatoid arthritis …

Since the description of age-associated or autoimmune-associated B cells (ABCs), there has
been a growing interest in the role of these cells in autoimmunity. ABCs are differently …