The introduction of trifluoromethylthio (SCF3) and trifluoromethylseleno (SeCF3)
substituents into organic molecules significantly improves the electron‐withdrawing and …

Aryl selenium, tellurium, arsenic and antimony compounds represent the privileged
structural scaffolds in synthetic chemistry for the construction of complex molecules from …

Use of attractive noncovalent interactions between ligand and substrate is an emerging
strategy for controlling positional selectivity. A key question relates to whether fine control on …

The development of innovative fluorination strategies is greatly dependent also on the
availability, safety and practicability of available fluorinating reagents. We herein show a …

While the modular construction of molecules from suitable building blocks is a powerful
means to more rapidly generate a diversity of molecules than through customized …

As significant pharmacophores, 1, 3-disubstituted cyclohexanes are widespread in natural
products and synthetic bioactive molecules. In this work, we describe a palladium-catalyzed …

The reaction of nucleophilic tertiary amines with trifluoromethyl and pentafluoroethyl methyl
ethers provides quaternary ammonium trifluoromethoxide (NR4OCF3) and …

Acyl chlorides are highly reactive and widely used substrates in catalytic cross-coupling
reactions, but so far, site selectivity over other functional groups has remained an issue. In …

The TeF5 group is significantly underexplored as a highly fluorinated substituent on an
organic framework, despite it being a larger congener of the acclaimed SF5 group. In fact …

While the N‐trifluoromethylation of cyclic ureas is of interest for the potential to
fundamentally change the properties of these biologically relevant moieties, the single …