Research during the past several decades has provided convincing evidence for a crucial
role of the Ca2+ ion in cell signaling. Hence, intracellular Ca2+ transients have been …

In the last years, clusterin, a challenging and paradoxical apolipoprotein, has been of
growing interest amongst a rising number of scientists. This enigmatic protein is present in …

Green tea catechins (GTCs) proved to be effective in inhibiting cancer growth in several
experimental models. Recent studies showed that 30% of men with high-grade prostate …

Clusterin, also known as apolipoprotein J, is a versatile chaperone molecule which contains
several amphipathic and coiled-coil α-helices, typical characteristics of small heat shock …

Clusterin/apolipoprotein J (CLU) gene has a nearly ubiquitous expression pattern in human
tissues. The two main CLU protein isoforms in human cells include the conventional …

Abstract Purpose: Secretory clusterin (sCLU)/apolipoprotein J is an extracellular chaperone
that has been functionally implicated in DNA repair, cell cycle regulation, apoptotic cell …

The multifaceted protein clusterin (CLU) has been challenging researchers for more than 35
years. The characterization of CLU as a molecular chaperone was one of the major …

The biological functions of clusterin (CLU, also known as ApoJ, SGP2, TRPM-2, CLI) have
been puzzling the researchers since its first discovery in the early 80's. We know that CLU is …

In recent years, Clusterin, a glycosylated protein with multiple biological functions, has
attracted extensive research attention. It is closely associated with the physiological and …

Proteomic studies on anticancer activity of Green Tea Catechins (specifically EGCG) are
suggesting a large set of protein targets that may directly interact with EGCG and alter the …