Aminoacyl-tRNA synthetase interactions in SARS-CoV-2 infection

D Khan, PL Fox - Biochemical Society Transactions, 2023 - portlandpress.com
Aminoacyl-tRNA synthetases (aaRSs) are ancient enzymes that serve a foundational role in
the efficient and accurate translation of genetic information from messenger RNA to proteins …

[HTML][HTML] Super-resolution proximity labeling reveals anti-viral protein network and its structural changes against SARS-CoV-2 viral proteins

YB Lee, M Jung, J Kim, A Charles, W Christ, J Kang… - Cell reports, 2023 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replicates in human cells
by interacting with host factors following infection. To understand the virus and host …

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface

S Datta, DY Chen, AH Tavares, T Reyes-Robles… - Cell Chemical …, 2023 - cell.com
Identifying virus-host interactions on the cell surface can improve our understanding of viral
entry and pathogenesis. SARS-CoV-2, the causative agent of the COVID-19 disease, uses …

Cellular proteomic profiling using proximity labeling by TurboID-NES in microglial and neuronal cell lines

S Sunna, C Bowen, H Zeng, S Rayaprolu… - Molecular & Cellular …, 2023 - ASBMB
Different brain cell types play distinct roles in brain development and disease. Molecular
characterization of cell-specific mechanisms using cell type–specific approaches at the …

Repurposing Proximity-Dependent Protein Labeling (BioID2) for Protein Interaction Mapping in E. coli

T Killelea, FE Kemm, L He, CJ Rudolph… - Cell Motility and …, 2024 - Springer
Methods that identify protein-protein interactions are essential for understanding molecular
mechanisms controlling biological systems. Proximity-dependent labeling has proven to be …

A genome-wide arrayed CRISPR screen identifies PLSCR1 as an intrinsic barrier to SARS-CoV-2 entry that recent virus variants have evolved to resist

J Le Pen, G Paniccia, V Kinast, M Moncada-Velez… - bioRxiv, 2024 - biorxiv.org
Interferons (IFNs) play a crucial role in the regulation and evolution of host-virus interactions.
Here, we conducted a genome-wide arrayed CRISPR knockout screen in the presence and …

An integrated approach using proximity labelling and chemical crosslinking to probe in situ host-virus protein–protein interactions

J Li, Z Lin - QRB discovery, 2024 - cambridge.org
Host-virus interactions are critically important for various stages of the viral replication cycle.
The reliance of viruses on the host factors for their entry, replication, and maturation …