Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

Manipulating fluids at varying length scales and understanding their underlying mechanisms
are significant for interdisciplinary studies of physics, chemistry, biology, and engineering; …

Solid-state nanopores are nm sized apertures formed in thin synthetic membranes. These
single molecule sensors have been used in a variety of biophysical and diagnostic …

Much more than ever, nucleic acids are recognized as key building blocks in many of lifeʼs
processes, and the science of studying these molecular wonders at the single-molecule …

Nanofabrication techniques for achieving dimensional control at the nanometer scale are
generally equipment-intensive and time-consuming. The use of energetic beams of …

A nanopore-based device provides single-molecule detection and analytical capabilities
that are achieved by electrophoretically driving molecules in solution through a nano-scale …

We report on DNA translocations through nanopores created in graphene membranes.
Devices consist of 1− 5 nm thick graphene membranes with electron-beam sculpted …

Nanopore systems have emerged as a leading platform for the analysis of biomolecular
complexes with single-molecule resolution. The conformation of biomolecules, such as …

Provided herein are methods and devices for characterizing a biomolecule parameter by a
nanopore-containing mem brane, and also methods for making devices that can be used in …

The transport of fluid in and around nanometer-sized objects with at least one characteristic
dimension below 100 nm enables the occurrence of phenomena that are impossible at …