Alzheimer's disease (AD) is a neurodegenerative disease with unknown pathogenesis and
complex pathological manifestations. At present, a large number of studies on targeted …

The advent of clustered regularly interspaced short palindromic repeat (CRISPR) has had a
profound impact on plant biology, and crop improvement. In this review, we summarize the …

Drought episodes decrease plant growth and productivity, which in turn cause high
economic losses. Plants naturally sense and respond to water stress by activating specific …

Oxygen, which is necessary for sustaining energy metabolism, is consumed in many
biochemical reactions in eukaryotes. When the oxygen supply is insufficient for maintaining …

The cellular mechanisms underlying hereditary photoreceptor degeneration are still poorly
understood, a problem that is exacerbated by the enormous genetic heterogeneity of this …

Therapeutic attempts to cure Alzheimer's disease (AD) have failed, and new strategies are
desperately needed. Motivated by this reality, many laboratories (including our own) have …

The histone acetylation modifications (HAMs) influence a large number of cellular functions.
They are mediated through histone acetyltransferase (HAT) and histone deacetylase …

Aging is a significant risk factor for Alzheimer's disease (AD), although the precise
mechanism and molecular basis of AD are not yet fully understood. Epigenetic mechanisms …

Memory impairment is the main feature of Alzheimer's disease (AD). Initial impairments
originate in the temporal lobe area and propagate throughout the brain in a sequential …

Short-chain acylations of lysine residues in eukaryotic proteins are recognized as essential
posttranslational chemical modifications (PTMs) that regulate cellular processes from …