[HTML][HTML] Seventy years of Chlamydia vaccine research–limitations of the past and directions for the future

S Phillips, BL Quigley, P Timms - Frontiers in microbiology, 2019 - frontiersin.org
Chlamydia is a major bacterial pathogen that infects humans, as well as a wide range of
animals, including marsupials, birds, cats, pigs, cattle, and sheep. Antibiotics are the only …

Chlamydial infections in wildlife–conservation threats and/or reservoirs of 'spill-over'infections?

D Burnard, A Polkinghorne - Veterinary microbiology, 2016 - Elsevier
Members of the order Chlamydiales are biphasic intracellular pathogens known to cause
disease in both humans and animals. As we learn more about the genetic diversity of this …

Automated detection of koalas using low-level aerial surveillance and machine learning

E Corcoran, S Denman, J Hanger, B Wilson… - Scientific reports, 2019 - nature.com
Effective wildlife management relies on the accurate and precise detection of individual
animals. These can be challenging data to collect for many cryptic species, particularly those …

Efficacy of a synthetic peptide Chlamydia pecorum major outer membrane protein vaccine in a wild koala (Phascolarctos cinereus) population

SJ Simpson, DP Higgins, P Timms, VSA Mella… - Scientific Reports, 2023 - nature.com
Chlamydiosis is a significant disease affecting Eastern Australian koala (Phascolarctos
cinereus) populations, impacting individual animal welfare and fecundity and therefore …

Infection with koala retrovirus subgroup B (KoRV-B), but not KoRV-A, is associated with chlamydial disease in free-ranging koalas (Phascolarctos cinereus)

CA Waugh, J Hanger, J Loader, A King, M Hobbs… - Scientific reports, 2017 - nature.com
The virulence of chlamydial infection in wild koalas is highly variable between individuals.
Some koalas can be infected (PCR positive) with Chlamydia for long periods but remain …

Helping koalas battle disease – Recent advances in Chlamydia and koala retrovirus (KoRV) disease understanding and treatment in koalas

BL Quigley, P Timms - FEMS Microbiology Reviews, 2020 - academic.oup.com
The iconic Australian marsupial, the koala (Phascolarctos cinereus), has suffered dramatic
population declines as a result of habitat loss and fragmentation, disease, vehicle collision …

Ecological and evolutionary challenges for wildlife vaccination

KM Barnett, DJ Civitello - Trends in Parasitology, 2020 - cell.com
Wildlife vaccination is of urgent interest to reduce disease-induced extinction and zoonotic
spillover events. However, several challenges complicate its application to wildlife. For …

Management of multiple threats achieves meaningful koala conservation outcomes

HL Beyer, D de Villiers, J Loader… - Journal of Applied …, 2018 - Wiley Online Library
Management actions designed to mitigate development or anthropogenic impacts on
species of conservation concern are often implemented without quantifying the benefit to the …

Dendrimer-conjugated peptide vaccine enhances clearance of Chlamydia trachomatis genital infection

IS Ganda, Q Zhong, M Hali, RLC Albuquerque… - International journal of …, 2017 - Elsevier
Peptide-based vaccines have emerged in recent years as promising candidates in the
prevention of infectious diseases. However, there are many challenges to maintaining in …

Immunization strategies producing a humoral IgG immune response against devil facial tumor disease in the majority of Tasmanian devils destined for wild release

R Pye, A Patchett, E McLennan, R Thomson… - Frontiers in …, 2018 - frontiersin.org
Devil facial tumor disease (DFTD) is renowned for its successful evasion of the host immune
system. Down regulation of the major histocompatabilty complex class I molecule (MHC-I) …