[HTML][HTML] Therapeutic application of quercetin in aging-related diseases: SIRT1 as a potential mechanism

Z Cui, X Zhao, FK Amevor, X Du, Y Wang, D Li… - Frontiers in …, 2022 - frontiersin.org
Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

[HTML][HTML] Polyphenol-mediated gut microbiota modulation: toward prebiotics and further

MC Rodríguez-Daza, EC Pulido-Mateos… - Frontiers in …, 2021 - frontiersin.org
The genome of gut microbes encodes a collection of enzymes whose metabolic functions
contribute to the bioavailability and bioactivity of unabsorbed (poly) phenols. Datasets from …

Gut microbiota markers associated with obesity and overweight in Italian adults

V Palmas, S Pisanu, V Madau, E Casula, A Deledda… - Scientific reports, 2021 - nature.com
In the present study, we characterized the distinctive signatures of the gut microbiota (GM)
from overweight/obese patients (OB), and normal-weight controls (NW), both of Sardinian …

[HTML][HTML] The role of polyphenols in human health and food systems: A mini-review

H Cory, S Passarelli, J Szeto, M Tamez, J Mattei - Frontiers in nutrition, 2018 - frontiersin.org
This narrative mini-review summarizes current knowledge of the role of polyphenols in
health outcomes–and non-communicable diseases specifically–and discusses the …

[HTML][HTML] Prebiotic effect of dietary polyphenols: A systematic review

AM Alves-Santos, CSA Sugizaki, GC Lima… - Journal of Functional …, 2020 - Elsevier
Prebiotics are substrates selectively metabolized by hindgut microorganisms conferring
health benefits. Recent studies suggest polyphenols as candidate to prebiotics. Thus, this …

Functional importance of bioactive compounds of foods with Potential Health Benefits: A review on recent trends

K Banwo, AO Olojede, AT Adesulu-Dahunsi, DK Verma… - Food Bioscience, 2021 - Elsevier
Researchers are nowadays focused on the importance of bioactive compounds (BACs) of
natural origin, which are secondary metabolites derived from seeds, food and fermentation …

High fat diet-triggered non-alcoholic fatty liver disease: A review of proposed mechanisms

CY Lian, ZZ Zhai, ZF Li, L Wang - Chemico-biological interactions, 2020 - Elsevier
Obesity is characterized by the deposition of excessive body fat, and is caused by energy
imbalance, especially when consuming fat-rich diets. High fat diet (HFD)-associated obesity …

Targeting mitochondrial ROS-mediated ferroptosis by quercetin alleviates high-fat diet-induced hepatic lipotoxicity

JJ Jiang, GF Zhang, JY Zheng, JH Sun… - Frontiers in …, 2022 - frontiersin.org
Background: The protective effect of quercetin on nonalcoholic fatty liver disease (NAFLD)
has been reported, but its mechanism remains poorly understood. Recently, quercetin was …

Exercise training modulates the gut microbiota profile and impairs inflammatory signaling pathways in obese children

R Quiroga, E Nistal, B Estébanez, D Porras… - … & molecular medicine, 2020 - nature.com
Childhood obesity has reached epidemic levels and is a serious health concern associated
with metabolic syndrome, nonalcoholic fatty liver disease, and gut microbiota alterations …

Alterations of lipid metabolism in cancer: implications in prognosis and treatment

LP Fernández, M Gomez de Cedron… - Frontiers in …, 2020 - frontiersin.org
Cancer remains the second leading cause of mortality worldwide. In the course of this
multistage and multifactorial disease, a set of alterations takes place, with genetic and …