Efficient Cas9‐based Genome Editing Using CRISPR Analysis Webtools in Severe Early‐onset‐obesity Patient‐derived iPSCs

A Patel, G Iannello, AG Diaz, D Sirabella… - Current …, 2022 - Wiley Online Library
The CRISPR system is an adaptive defense mechanism used by bacteria and archaea
against viruses and plasmids. The discovery of the CRISPR‐associated protein Cas9 and its …

[HTML][HTML] Derivation and characterization of the induced pluripotent stem cell line CUIMCi004-A from a patient with a novel frameshift variant in exon 18a of OCRL

G Iannello, A Patel, D Sirabella, B Corneo, VV Thaker - Stem cell research, 2022 - Elsevier
OCRL encodes for an inositol polyphosphate 5-phosphatase, located in the trans-Golgi
network, endosomes, endocytic clathrin-coated pits, primary cilia. Mutations in OCRL causes …