Photolabile Protecting Groups Based on the Excited State Meta Effect: Development and Application

P Wang, C Lim - Photochemistry and Photobiology, 2023 - Wiley Online Library
This review focuses on utilization of the excited state meta effect (ESME) in the development
of photolabile protecting groups (PPGs). Structurally simple ESME‐based PPGs for release …

Synthesis of Benzoaryl-5-yl(2-hydroxyphenyl)methanones via Photoinduced Rearrangement of (E)-3-Arylvinyl-4H-chromen-4-ones

J Fan, T Wang, C Li, R Wang, X Lei, Y Liang… - Organic …, 2017 - ACS Publications
A concise and efficient photoinduced rearrangement of (E)-3-arylvinyl-4 H-chromen-4-ones
for the synthesis of benzoaryl-5-yl (2-hydroxyphenyl) methanones is described. Benzoaryl-5 …

New SIRT2 inhibitors: Histidine-based bleomycin spin-off

TFS Ali, HI Ciftci, MO Radwan, R Koga, T Ohsugi… - Bioorganic & Medicinal …, 2019 - Elsevier
Bleomycin is considered to exert its antitumor activity via DNA cleavage mediated by
activated oxygen generated from the iron complex in its chelator moiety. Spin-offs from this …

Developing photolabile protecting groups based on the excited state meta effect

P Wang - Journal of Photochemistry and Photobiology A …, 2017 - Elsevier
We have recently developed a number of photolabile protecting groups (PPGs) for efficient
release of carbonyl, hydroxyl, diol, carboxyl, and amino functionalities. These new PPGs are …

Photochemical Cleavage of Benzylic C–O Bond Facilitated by an Ortho or Meta Amino Group

X Ding, P Wang - The Journal of organic chemistry, 2017 - ACS Publications
The excited state meta effect, also known as the meta-ortho effect, results from selective
electron transmission from an electron-donating group to the meta and ortho sites on an …

A water soluble light activated hydrogen sulfide donor induced by an excited state meta effect

M Bera, S Maji, A Paul, S Ray, TK Maiti… - Organic & Biomolecular …, 2019 - pubs.rsc.org
We have utilized an m-amino benzyl based photoremovable protecting group (PRPG) to
develop a new water soluble H2S donor. It efficiently releases H2S on demand in a spatio …

1, 4-Dithiothreitol mediated cleavage of the acetal and ketal type of diol protecting groups

Y Liu, J Zeng, J Sun, L Cai, Y Zhao, J Fang… - Organic Chemistry …, 2018 - pubs.rsc.org
The use of 1, 4-dithiothreitol (DTT) as an acetal or ketal exchange reagent and
camphorsulfonic acid (CSA) as a catalyst permitted the efficient removal of benzylidene …

Using the 3-diethylaminobenzyl group as a photocage in aqueous solution

X Ding, P Wang - The Journal of organic chemistry, 2018 - ACS Publications
We have demonstrated that the 3-diethylaminobenzyl (DEABn) photolabile protecting group
(PPG) is an effective and structurally simple PPG for releasing molecules in aqueous …

Glycosides, Synthesis and Characterization

M Brito-Arias - Synthesis and characterization of glycosides, 2022 - Springer
Monosaccharidesare generally definedas aldosesand ketoses connected to a poly
hydroxylated skeleton (Robyt in Essentials of Carbohydrate Chemistry, Springer, NY, 1998) …

Conception d'hydrogels à la composition et aux propriétés mécaniques ajustables pour l'étude des interactions cellules-matériaux et l'amélioration de la thérapie …

N Lagneau - 2022 - theses.hal.science
En raison de leur capacité à sécréter divers agents thérapeutiques, les cellules stromales
mésenchymateuses (CSMs), constituent un outil thérapeutique prometteur pour le traitement …