An overview of polyallylamine applications in gene delivery

L Gholami, A Mahmoudi… - Pharmaceutical …, 2022 - Taylor & Francis
A chief objective of gene transportation studies is to manipulate clinically accepted carriers
that can be utilized to combat incurable diseases. Despite various strategies, efficiency and …

Addressing specific (poly) ion effects for layer-by-layer membranes

D Scheepers, A Casimiro, Z Borneman… - ACS Applied Polymer …, 2023 - ACS Publications
Layer-by-layer (LbL) assembly of the alternating adsorption of oppositely charged polyions
is an extensively studied method to produce nanofiltration membranes. In this work, the …

Enhanced antibacterial activity of se nanoparticles upon coating with recombinant spider silk protein eADF4 (κ16)

T Huang, S Kumari, H Herold, H Bargel… - International Journal …, 2020 - Taylor & Francis
Purpose Selenium nanoparticles (Se NPs) are promising antibacterial agents to tackle the
growing problem of antimicrobial resistance. The aim of this study was to fabricate Se NPs …

Effect of polycation nanostructures on cell membrane permeability and toxicity

M Wytrwal-Sarna, P Knobloch, S Lasota… - Environmental …, 2022 - pubs.rsc.org
The interaction of nanometric synthetic materials with cell membranes is one of the key
factors determining their possible cytotoxicity. This work investigated the interaction of …

Polycation–anionic lipid membrane interactions

W Kopec, A Zak, D Jamróz, R Nakahata, S Yusa… - Langmuir, 2020 - ACS Publications
Natural or synthetic polycations are used as biocides or as drug/gene carriers.
Understanding the interactions between these macromolecules and cell membranes at the …

Adsorption of synthetic cationic polymers on model phospholipid membranes: Insight from atomic-scale molecular dynamics simulations

AY Kostritskii, DA Kondinskaia, AM Nesterenko… - Langmuir, 2016 - ACS Publications
Although synthetic cationic polymers represent a promising class of effective antibacterial
agents, the molecular mechanisms behind their antimicrobial activity remain poorly …

A therapeutic polyelectrolyte–vitamin C nanoparticulate system in polyvinyl alcohol–alginate hydrogel: An approach to treat skin and soft tissue infections caused by …

L George, MC Bavya, KV Rohan… - Colloids and Surfaces B …, 2017 - Elsevier
Staphylococcus aureus infections affecting the skin and soft tissues are of significant health
concern and an unmet need to be addressed. The lack of drug penetration into the infectious …

Targeting of the kynurenic acid across the blood–brain barrier by core-shell nanoparticles

N Varga, E Csapó, Z Majláth, I Ilisz, IA Krizbai… - European Journal of …, 2016 - Elsevier
Core-shell nanoparticles (CSNPs) were developed to get over therapeutic amount of
kynurenic acid (KYNA) across the blood–brain barrier (BBB). Bovine serum albumin (BSA) …

Interactions of polyethylenimines with zwitterionic and anionic lipid membranes

U Kwolek, D Jamróz, M Janiczek, M Nowakowska… - Langmuir, 2016 - ACS Publications
Interactions between polyethylenimines (PEIs) and phospholipid membranes are of
fundamental importance for various biophysical applications of these polymers such as …

Effect of polycation structure on interaction with lipid membranes

N Wilkosz, D Jamróz, W Kopec, K Nakai… - The Journal of …, 2017 - ACS Publications
Interaction of polycations with lipid membranes is a very important issue in many biological
and medical applications such as gene delivery or antibacterial usage. In this work, we …