Metal/covalent-organic framework-based biosensors for nucleic acid detection

ZW Yang, JJ Li, YH Wang, FH Gao, JL Su, Y Liu… - Coordination Chemistry …, 2023 - Elsevier
The detection of nucleic acid marker is essential for accurate and timely diagnosis and
prognosis of different types of diseases. However, the sensitivity and specificity of the assay …

[HTML][HTML] Could chronic HBV infection explain Beethoven's hearing loss? Implications for patients currently living with hepatitis B

P Rzymski, D Zarębska-Michaluk, R Flisiak - Journal of Infection, 2023 - Elsevier
The cause of Ludwig van Beethoven's health deterioration, ie, hearing loss and cirrhosis,
have been subject to various studies. The genomic analysis of his hair indicates infection …

Advancing beyond reverse transcriptase inhibitors: The new era of hepatitis B polymerase inhibitors

A Ranga, A Gupta, L Yadav, S Kumar, P Jain - European Journal of …, 2023 - Elsevier
Hepatitis B virus (HBV) is a genetically diverse blood-borne virus responsible for chronic
hepatitis B. The HBV polymerase plays a key role in viral genome replication within the …

ARRDC3 inhibits liver fibrosis and epithelial-to-mesenchymal transition via the ITGB4/PI3K/Akt signaling pathway

B Zhang, F Wu, P Li, H Li - Immunopharmacology and …, 2023 - Taylor & Francis
Objective The effect of ARRDC3 has not been reported in liver fibrosis. Our study aimed to
explore the molecular mechanisms by which ARRDC3 attenuates liver fibrosis. Methods The …

Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC

W Shi, K Li, Y Zhang - Frontiers in Oncology, 2023 - frontiersin.org
Chronic hepatitis B virus (HBV) infection is a worldwide public health threat that results in
huge morbidity and mortality. Late diagnosis and delayed treatment of HBV infections can …

Biology of the hepatitis B virus (HBV) core and capsid assembly modulators (CAMs) for chronic hepatitis B (CHB) cure

WM McFadden, SG Sarafianos - Global Health & Medicine, 2023 - jstage.jst.go.jp
Hepatitis B virus (HBV) is a hepadnavirus, a small DNA virus that infects liver tissue, with
some unusual replication steps that share similarities to retroviruses. HBV infection can lead …

HBCVTr: an end-to-end transformer with a deep neural network hybrid model for anti-HBV and HCV activity predictor from SMILES

I Meewan, J Panmanee, N Petchyam, P Lertvilai - Scientific Reports, 2024 - nature.com
Hepatitis B and C viruses (HBV and HCV) are significant causes of chronic liver diseases,
with approximately 350 million infections globally. To accelerate the finding of effective …

Global prevalence and molecular characteristics of three clades within hepatitis B virus subgenotype C2: Predominance of the C2 (3) clade in South Korea

DH Kim, YM Choi, J Jang, BJ Kim - Frontiers in microbiology, 2023 - frontiersin.org
Hepatitis B Virus (HBV) genotypes reflect geographic, ethical or clinical traits and are
currently divided into 10 genotypes (A–J). Of these, genotype C is mainly distributed in Asia …

Phytomedicines to target hepatitis B virus DNA replication: current limitations and future approaches

RZ Sadiea, S Sultana, BM Chaki, T Islam… - International Journal of …, 2022 - mdpi.com
Hepatitis B virus infection (HBV) is one of the most common causes of hepatitis, and may
lead to cirrhosis or hepatocellular carcinoma. According to the World Health Organization …

The Epidemiology, Transmission, Genotypes, Replication, Serologic and Nucleic Acid Testing, Immunotolerance, and Reactivation of Hepatitis B Virus

A Patel, Z Dossaji, K Gupta, K Roma, TM Chandler… - Gastro Hep …, 2023 - Elsevier
The epidemiology of HBV has drastically changed in recent decades due to public health
initiatives, including universal infant vaccination programs and urbanization driving global …