Flow and particle modelling of dry powder inhalers: Methodologies, recent development and emerging applications

Z Zheng, SSY Leung, R Gupta - Pharmaceutics, 2021 - mdpi.com
Dry powder inhaler (DPI) is a device used to deliver a drug in dry powder form to the lungs.
A wide range of DPI products is currently available, with the choice of DPI device largely …

Numerical investigation of the hydraulic transport of coarse particles in a vertical pipe based on a fully-coupled numerical model

R Zhao, Y Zhou, D Zhang, X Gao - International Journal of Multiphase Flow, 2022 - Elsevier
The hydraulic transport of coarse particles in a vertical pipe is simulated in this work and the
influences of different mechanisms of the fluid-particle interactions on the liquid-solid flow …

[HTML][HTML] Coupling CFD-DEM with dynamic meshing: A new approach for fluid-structure interaction in particle-fluid flows

Y He, AE Bayly, A Hassanpour - Powder Technology, 2018 - Elsevier
Many important engineering applications involve the interaction of free-moving objects with
dispersed multi-phase flows, however due to the challenge and complexity of modelling …

A critical review of physical models in high temperature multiphase fluid dynamics: Turbulent transport and particle-wall interactions

N Jain, A Le Moine… - Applied …, 2021 - asmedigitalcollection.asme.org
This review article examines the last decade of studies investigating solid, molten, and liquid
particle interactions with one another and with walls in heterogeneous multiphase flows …

A multiscale DEM-VOF method for the simulation of three-phase flows

G Pozzetti, B Peters - International Journal of Multiphase Flow, 2018 - Elsevier
A novel multiscale approach for three-phase flows is presented. The goal of the proposed
method is to solve arbitrary three-phase flow configurations in a computationally efficient …

Theoretical analysis of acoustic and turbulent agglomeration of droplet aerosols

Y Shi, J Wei, W Bai, Z Zhao, OO Ayantobo… - Advanced Powder …, 2023 - Elsevier
This study meticulously explores the agglomeration mechanisms in microscale droplet
aerosols, specifically focusing on acoustic and turbulent agglomeration mechanisms. Our …

CFD–DEM simulation of pneumatic conveying in a horizontal channel

H Zhao, Y Zhao - International Journal of Multiphase Flow, 2019 - Elsevier
In this paper, the pneumatic conveying in a horizontal channel is simulated by the combined
approach of computational fluid dynamics (CFD) and discrete element method (DEM). A …

Numerical study of diesel particulate matter distribution in an underground mine isolated zone

G Xu, P Chang, B Mullins, F Zhou, S Hu - Powder technology, 2018 - Elsevier
The increased use of diesel engines in underground mines, together with increased mine
depth, cause challenges in maintaining diesel particulate matter (DPM) at acceptable levels …

Pneumatic conveying of cohesive dairy powder: Experiments and CFD-DEM simulations

AK Olaleye, O Shardt, GM Walker… - Powder Technology, 2019 - Elsevier
We performed an experimental and numerical investigation of pneumatic conveying of
cohesive dairy powder. The experiments with fat-filled milk powder (FFMP) fines with an …

[HTML][HTML] Erosive wear and particle attrition in multi-stage solar particle receivers and screw conveyors: A CFD-DEM approach with machine learning and artificial …

STW Kuruneru, JS Kim - Chemical Engineering Science, 2024 - Elsevier
A coupled finite volume and discrete element method (CFD-DEM) numerical model is
developed to unravel the fundamental mechanisms of granular transport, surface erosive …