Role of inflammation in the pathogenesis of osteoarthritis: latest findings and interpretations

J Sokolove, CM Lepus - Therapeutic advances in …, 2013 - journals.sagepub.com
Osteoarthritis (OA) has traditionally been classified as a noninflammatory arthritis; however,
the dichotomy between inflammatory and degenerative arthritis is becoming less clear with …

Contribution of infrapatellar fat pad and synovial membrane to knee osteoarthritis pain

E Belluzzi, E Stocco, A Pozzuoli… - BioMed research …, 2019 - Wiley Online Library
Osteoarthritis (OA) is the most common form of joint disease and a major cause of pain and
disability in the adult population. Interestingly, there are patients with symptomatic OA …

[HTML][HTML] The infrapatellar fat pad should be considered as an active osteoarthritic joint tissue: a narrative review

S Clockaerts, YM Bastiaansen-Jenniskens… - Osteoarthritis and …, 2010 - Elsevier
INTRODUCTION: Osteoarthritis (OA) of the knee joint is caused by genetic and hormonal
factors and by inflammation, in combination with biomechanical alterations. It is …

The infrapatellar fat pad in inflammaging, knee joint health, and osteoarthritis

MG Wang, P Seale, D Furman - npj Aging, 2024 - nature.com
Osteoarthritis (OA) is the most common form of arthritis and accounts for nearly $140 billion
in annual healthcare expenditures only in the United States. Obesity, aging, and joint injury …

Cd10-Bound human mesenchymal stem/stromal cell-derived small extracellular vesicles possess immunomodulatory cargo and maintain cartilage homeostasis under …

D Kouroupis, LD Kaplan, J Huard, TM Best - Cells, 2023 - mdpi.com
The onset and progression of human inflammatory joint diseases are strongly associated
with the activation of resident synovium/infrapatellar fat pad (IFP) pro-inflammatory and pain …

[HTML][HTML] Infrapatellar fat pad and knee osteoarthritis

N Zeng, ZP Yan, XY Chen, GX Ni - Aging and disease, 2020 - ncbi.nlm.nih.gov
Osteoarthritis is the most prevalent arthritis typically characterized by degradation of
cartilage. However, its pathogenesis is not fully understood. Currently, osteoarthritis is best …

The infrapatellar fat pad and the synovial membrane: an anatomo‐functional unit

V Macchi, E Stocco, C Stecco, E Belluzzi… - Journal of …, 2018 - Wiley Online Library
The infrapatellar pad, a fibro‐adipose tissue with peculiar microscopic and mechanical
features, is gaining wide attention in the field of rheumatological research. The purpose of …

Evaluation and treatment of disorders of the infrapatellar fat pad

JL Dragoo, C Johnson, J McConnell - Sports medicine, 2012 - Springer
The infrapatellar fat pad (IFP), also known as Hoffa's fat pad, is an intracapsular,
extrasynovial structure that fills the anterior knee compartment, and is richly vascularized …

The role of obesity and adipose tissue dysfunction in osteoarthritis pain

M Binvignat, J Sellam, F Berenbaum… - Nature Reviews …, 2024 - nature.com
Obesity has a pivotal and multifaceted role in pain associated with osteoarthritis (OA),
extending beyond the mechanistic influence of BMI. It exerts its effects both directly and …

Gait changes in patients with knee osteoarthritis are replicated by experimental knee pain

M Henriksen, T Graven‐Nielsen, J Aaboe… - Arthritis care & …, 2010 - Wiley Online Library
Objective Medial knee osteoarthritis (OA) is characterized by pain and associated with
abnormal knee moments during walking. The relationship between knee OA pain and gait …