The factor that is most relevant and strongly associated with the clinical course of multiple
sclerosis is chronological age. Very young patients exclusively have relapsing remitting …

Multiple sclerosis (MS) is an autoimmune disease affecting the central nervous system that
causes significant disability and healthcare burden. The treatment of MS has evolved over …

Aging is characterized, amongst other features, by a complex process of cellular
senescence involving both innate and adaptive immunity, called immunosenescence and …

Aging is associated with a progressive decline of innate and adaptive immune responses,
called immunosenescence. This phenomenon links to different multiple sclerosis (MS) …

Telomeres are protective structures at the ends of linear chromosomes. Shortened telomere
lengths (TL) are an indicator of premature biological aging and have been associated with a …

Objectives Multiple sclerosis (MS) is a chronic inflammatory autoimmune and degenerative
disorder of the central nervous system. Telomeres are protective structures located at the …

Telomeres are protective cap structures at the end of chromosomes that are essential for
maintaining genomic stability. Accelerated telomere shortening is related to premature …

The neuroinflammatory disease multiple sclerosis is driven by autoimmune pathology in the
central nervous system. However, the trigger of the autoimmune pathogenic process is …

Abstract Changes in the immune system associated with ageing are known as
immunosenescence. This is characterised by a decline in immune response, chronic …

The aging of the immune system has recently attracted a lot of attention. Immune
senescence describes changes that the immune system undergoes over time. The …