Sleep is critical for diverse aspects of brain function in animals ranging from invertebrates to
humans. Powerful genetic tools in the fruit fly Drosophila melanogaster have identified—at …

The advantages of the model organism Drosophila melanogaster, including low genetic
redundancy, functional simplicity, and the ability to conduct large-scale genetic screens …

Making inferences about the computations performed by neuronal circuits from synapse-
level connectivity maps is an emerging opportunity in neuroscience. The mushroom body …

Sleep is thought to be restorative to brain energy homeostasis, but it is not clear how this is
achieved. We show here that Drosophila glia exhibit a daily cycle of glial mitochondrial …

Understanding memory formation, storage and retrieval requires knowledge of the
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …

Little is known about the ability of Drosophila circadian neurons to promote sleep. Here we
show, using optogenetic manipulation and video recording, that a subset of dorsal clock …

Associative learning is thought to involve parallel and distributed mechanisms of memory
formation and storage. In Drosophila, the mushroom body (MB) is the major site of …

Employing the clear, student-friendly style that made previous editions so popular, Insect
Physiology and Biochemistry, Fourth Edition presents an engaging and authoritative guide …

Despite decades of intense study, the functions of sleep are still shrouded in mystery. The
difficulty in understanding these functions can be at least partly attributed to the varied …

High-resolution electron microscopy of nervous systems has enabled the reconstruction of
synaptic connectomes. However, we do not know the synaptic sign for each connection (ie …