Long covid—mechanisms, risk factors, and management
Since its emergence in Wuhan, China, covid-19 has spread and had a profound effect on
the lives and health of people around the globe. As of 4 July 2021, more than 183 million …
the lives and health of people around the globe. As of 4 July 2021, more than 183 million …
Association between mood disorders and risk of COVID-19 infection, hospitalization, and death: a systematic review and meta-analysis
Importance Preexisting noncommunicable diseases (eg, diabetes) increase the risk of
COVID-19 infection, hospitalization, and death. Mood disorders are associated with …
COVID-19 infection, hospitalization, and death. Mood disorders are associated with …
[HTML][HTML] Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform …
G Reis, EA dos Santos Moreira-Silva… - The Lancet Global …, 2022 - thelancet.com
Background Recent evidence indicates a potential therapeutic role of fluvoxamine for
COVID-19. In the TOGETHER trial for acutely symptomatic patients with COVID-19, we …
COVID-19. In the TOGETHER trial for acutely symptomatic patients with COVID-19, we …
Potential therapeutic options for COVID-19: an update on current evidence
Abstract SARS-CoV-2, a novel coronavirus, is the agent responsible for the COVID-19
pandemic and is a major public health concern nowadays. The rapid and global spread of …
pandemic and is a major public health concern nowadays. The rapid and global spread of …
Mechanisms of action of fluvoxamine for COVID-19: a historical review
Y Hashimoto, T Suzuki, K Hashimoto - Molecular psychiatry, 2022 - nature.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accelerates the discovery of …
The association of smoking status with SARS‐CoV‐2 infection, hospitalization and mortality from COVID‐19: a living rapid evidence review with Bayesian meta …
Aims To estimate the association of smoking status with rates of (i) infection,(ii)
hospitalization,(iii) disease severity and (iv) mortality from SARS‐CoV‐2/COVID‐19 disease …
hospitalization,(iii) disease severity and (iv) mortality from SARS‐CoV‐2/COVID‐19 disease …
[HTML][HTML] Fluvoxamine: a review of its mechanism of action and its role in COVID-19
Fluvoxamine is a well-tolerated, widely available, inexpensive selective serotonin reuptake
inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized …
inhibitor that has been shown in a small, double-blind, placebo-controlled, randomized …
Mortality risk among patients with COVID-19 prescribed selective serotonin reuptake inhibitor antidepressants
Importance Antidepressant use may be associated with reduced levels of several
proinflammatory cytokines suggested to be involved with the development of severe COVID …
proinflammatory cytokines suggested to be involved with the development of severe COVID …
Pharmacological inhibition of acid sphingomyelinase prevents uptake of SARS-CoV-2 by epithelial cells
A Carpinteiro, MJ Edwards, M Hoffmann, G Kochs… - Cell Reports …, 2020 - cell.com
The acid sphingomyelinase/ceramide system plays an important role in bacterial and viral
infections. Here, we report that either pharmacological inhibition of acid sphingomyelinase …
infections. Here, we report that either pharmacological inhibition of acid sphingomyelinase …
The acid sphingomyelinase/ceramide system in COVID-19
J Kornhuber, N Hoertel, E Gulbins - Molecular Psychiatry, 2022 - nature.com
Acid sphingomyelinase (ASM) cleaves sphingomyelin into the highly lipophilic ceramide,
which forms large gel-like rafts/platforms in the plasma membrane. We showed that SARS …
which forms large gel-like rafts/platforms in the plasma membrane. We showed that SARS …