The role of the medial prefrontal cortex in cognition, ageing and dementia

DD Jobson, Y Hase, AN Clarkson… - Brain …, 2021 - academic.oup.com
Humans require a plethora of higher cognitive skills to perform executive functions, such as
reasoning, planning, language and social interactions, which are regulated predominantly …

Functional connectivity changes in cerebral small vessel disease-a systematic review of the resting-state MRI literature

M Schulz, C Malherbe, B Cheng, G Thomalla… - BMC medicine, 2021 - Springer
Background Cerebral small vessel disease (CSVD) is a common neurological disease
present in the ageing population that is associated with an increased risk of dementia and …

[HTML][HTML] Brain network disintegration as a final common pathway for delirium: a systematic review and qualitative meta-analysis

SJT Van Montfort, E Van Dellen, CJ Stam… - NeuroImage: Clinical, 2019 - Elsevier
Delirium is an acute neuropsychiatric syndrome characterized by altered levels of attention
and awareness with cognitive deficits. It is most prevalent in elderly hospitalized patients …

Disrupted topological organization of resting‐state functional brain networks in cerebral small vessel disease

H Xin, H Wen, M Feng, Y Gao, C Sui… - Human Brain …, 2022 - Wiley Online Library
We aimed to investigate alterations in functional brain networks and assess the relationship
between functional impairment and topological network changes in cerebral small vessel …

The application of rs-fMRI in vascular cognitive impairment

R Wang, N Liu, YY Tao, XQ Gong, J Zheng… - Frontiers in …, 2020 - frontiersin.org
The incidence of vascular cognitive impairment (VCI) has been increasing for years and has
become a major disabling factor in middle-aged and elderly populations. The pathogenesis …

Predicting future learning from baseline network architecture

MG Mattar, NF Wymbs, AS Bock, GK Aguirre… - NeuroImage, 2018 - Elsevier
Human behavior and cognition result from a complex pattern of interactions between brain
regions. The flexible reconfiguration of these patterns enables behavioral adaptation, such …

Diagnostic efficacy of voxel-mirrored homotopic connectivity in vascular dementia as compared to alzheimer's related neurodegenerative diseases—A resting state …

EYW Cheung, YF Shea, PKC Chiu, JSK Kwan… - Life, 2021 - mdpi.com
Previous studies have demonstrated that functional connectivity (FC) of different brain
regions in resting state function MRI were abnormal in patients suffering from mild cognitive …

Association of age and structural brain changes with functional connectivity and executive function in a middle-aged to older population-based cohort

M Schulz, C Mayer, E Schlemm, BM Frey… - Frontiers in Aging …, 2022 - frontiersin.org
Aging is accompanied by structural brain changes that are thought to underlie cognitive
decline and dementia. Yet little is known regarding the association between increasing age …

Characterizing brain iron deposition in patients with subcortical vascular mild cognitive impairment using quantitative susceptibility mapping: a potential biomarker

Y Sun, X Ge, X Han, W Cao, Y Wang, W Ding… - Frontiers in Aging …, 2017 - frontiersin.org
The presence and pattern of iron accumulation in subcortical vascular mild cognitive
impairment (svMCI) and their effects on cognition have rarely been investigated. We aimed …

Cortical and subcortical grey matter abnormalities in white matter hyperintensities and subsequent cognitive impairment

W Zhu, H Huang, S Yang, X Luo, W Zhu, S Xu… - Neuroscience …, 2021 - Springer
Grey matter (GM) alterations may contribute to cognitive decline in individuals with white
matter hyperintensities (WMH) but no consensus has yet emerged. Here, we investigated …