[HTML][HTML] Development and Application of Automated Sandwich ELISA for Quantitating Residual dsRNA in mRNA Vaccines
DA Holland, J Acevedo-Skrip, J Barton, R Thompson… - Vaccines, 2024 - mdpi.com
The rise of mRNA as a novel vaccination strategy presents new opportunities to confront
global disease. Double-stranded RNA (dsRNA) is an impurity byproduct of the in vitro …
global disease. Double-stranded RNA (dsRNA) is an impurity byproduct of the in vitro …
[HTML][HTML] Explore the action mechanism of Danggui Buxue decoction on chronic heart failure in rats by proteomics and untargeted metabolomics
Y Zhou, Y Guan, S Tao, Z Pu, K Yang, J Qi… - Journal of Traditional …, 2024 - Elsevier
Abstract Background and aim Danggui Buxue Decoction (DBD) has been applied to
alleviate chronic heart failure (CHF) in clinics, however, its mechanism is still unclear. This …
alleviate chronic heart failure (CHF) in clinics, however, its mechanism is still unclear. This …
[HTML][HTML] Automated, Quantitative Capillary Western Blots to Analyze Host Cell Proteins in COVID-19 Vaccine Produced in Vero Cell Line
PF Gillespie, Y Wang, K Yin, E Groegler… - Vaccines, 2024 - mdpi.com
Background/Objectives: Host cell protein (HCP) content is a major attribute for biological and
vaccine products that must be extensively characterized prior to product licensure. Enzyme …
vaccine products that must be extensively characterized prior to product licensure. Enzyme …
Detection of residual T7 RNA polymerase used in mRNA in vitro transcription by Simple Western
Y Shieh, AR Swartz, RR Rustandi - ELECTROPHORESIS, 2024 - Wiley Online Library
Therapeutic messenger RNA (mRNA) has been demonstrated as a scalable and versatile
vaccine platform for the rapid development and manufacture of new vaccine candidates …
vaccine platform for the rapid development and manufacture of new vaccine candidates …
Expression system and purification process for the vaccine production
Vaccine production is growing significantly every day. Immunization has regained its critical
importance, particularly after the occurrence of the SARS-CoV-2 pandemic. When the entire …
importance, particularly after the occurrence of the SARS-CoV-2 pandemic. When the entire …