Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …

Oxidative stress reflects a disturbance in the balance between the production and
accumulation of reactive oxygen species (ROS). ROS are scavenged by the antioxidant …

Reactive oxygen species (ROS) are continuously produced in living cells due to metabolic
and biochemical reactions and due to exposure to physical, chemical and biological agents …

Generation of oxidatively damaged DNA by particulate matter (PM) is hypothesized to occur
via production of reactive oxygen species (ROS) and inflammation. We investigated this …

Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …

Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …

Despite the long held hypothesis that oxidant stress results in accumulated oxidative
damage to cellular macromolecules and subsequently to aging and age-related chronic …

Chronic inflammation has long been recognized as a risk factor for many human cancers.
One mechanistic link between inflammation and cancer involves the generation of nitric …

The past decade has provided exciting insights into a novel class of central (small) RNA
molecules intimately involved in gene regulation. Only a small percentage of our DNA is …

Abstract Aims: Urinary 8-oxo-7, 8-dihydro-2′-deoxyguanosine (8-oxodG) is a widely used
biomarker of oxidative stress. However, variability between chromatographic and ELISA …