S100 is a broad subfamily of low-molecular weight calcium-binding proteins (9–14 kDa) with
structural similarity and functional discrepancy. It is required for inflammation and cellular …

The receptor for advanced glycation end products (RAGE) is a non-specific multi-ligand
pattern recognition receptor capable of binding to a range of structurally diverse ligands …

Alzheimer's disease (AD) pathologies were discovered in the accessible neurosensory
retina. However, their exact nature and topographical distribution, particularly in the early …

In neurodegenerative diseases, extracellular vesicles (EVs) transfer pathogenic molecules
and are consequently involved in disease progression. We have investigated the proteomic …

Alzheimer's disease (AD) is a debilitating neurological disorder, and currently, there is no
cure for it. Several pathologic alterations have been described in the brain of AD patients …

The intestinal microbiome releases a plethora of small molecules. Here, we show that the
Ruminococcaceae metabolite isoamylamine (IAA) is enriched in aged mice and elderly …

The amyloid hypothesis has dominated Alzheimer's disease (AD) research for almost 30
years. This hypothesis hinges on the predominant clinical role of the amyloid beta (Aβ) …

Atomic force microscopy (AFM) imaging enables the visualization of protein molecules with
high resolution, providing insights into their shape, size, and surface topography. Here, we …

S100 proteins are widely expressed small molecular EF-hand calcium-binding proteins of
vertebrates, which are involved in numerous cellular processes, such as Ca2+ homeostasis …

Abstract Prometryn, 2-methylthio-4, 6-bis (isopropylamino)-1, 3, 5-triazine, is a selective
thiomethyl triazine herbicide widely used to control unwanted weeds and harmful insects by …