Synthesis of heterocyclic compounds via Michael and Hantzsch reactions

AM Abdella, AM Abdelmoniem… - Journal of …, 2020 - Wiley Online Library
Heterocycles represent the largest diversity of organic compounds with signifcant chemical,
biomedical, and industrial applications. They exist in numerous natural products, dyes, and …

A comprehensive survey upon diverse and prolific applications of chitosan-based catalytic systems in one-pot multi-component synthesis of heterocyclic rings

H Mousavi - International Journal of Biological Macromolecules, 2021 - Elsevier
Heterocyclic compounds are among the most prestigious and valuable chemical molecules
with diverse and magnificent applications in various sciences. Due to the remarkable and …

Molecular docking simulation and anticancer assessment on human breast carcinoma cell line using novel bis (1, 4-dihydropyrano [2, 3-c] pyrazole-5-carbonitrile) and …

SK Salama, MF Mohamed, AF Darweesh… - Bioorganic …, 2017 - Elsevier
An efficient route for the synthesis of novel bis (1, 4-dihydropyrano [2, 3-c] pyrazole-5-
carbonitrile) derivatives is reported. The synthetic pathway involves one pot, synthesis of bis …

Synthesis, characterization, DNA photocleavage, in silico and in vitro DNA/BSA binding properties of novel hexahydroquinolines

MA Ragheb, RS Omar, MH Soliman… - Journal of Molecular …, 2022 - Elsevier
A simple, and efficient procedure has been developed for the synthesis of novel 2-(4-
(hexahydroquinolin-4-yl) phenoxy)-N-arylacetamides and thieno [3′, 2′: 5, 6] pyrimido [1 …

Synthesis of novel bis (spirocyclic-2-oxindole)-tethered 10b-azachrysene or 10a-azaphenanthrene systems via a Hantzsch-like reaction

AM Abdelmoniem, IA Abdelhamid, AHM Elwahy… - Tetrahedron, 2024 - Elsevier
The effective synthesis of bis (spirocyclic-2-oxindole) tethered to 10b-azachrysene or 10a-
azaphenanthrene moieties via the Hantzsch-like reaction of phenylenebis (methylene)) bis …

Hantzsch‐like synthesis of isoquinolino[2,1‐a]quinoline‐12‐carbonitrile incorporating aryl or heteroaryl moieties at C‐13

MA Mohamed Teleb, HM Hassaneen… - Journal of …, 2024 - Wiley Online Library
The synthesis of a new series of the tetracyclic 13‐arylisoquinolino [2, 1‐a] quinoline‐12‐
carbonitrile has been accomplished using a straightforward and efficient method. The novel …

[HTML][HTML] Synthesis of novel star-shaped molecules based on a pentaerythritol core linked to different heterocyclic systems

HM Diab, IA Abdelhamid, ME Salem, I Ragab… - Results in …, 2024 - Elsevier
Synthesis of analogs of known active compounds is the most often employed strategy for
producing important compounds. The Hantzsch reaction was employed to create new star …

Synthesis of novel dihydropyridine, fused dihydropyridines, hexahydrobenzo[4,5]imidazo[2,1-b]quinazolines, and fused-pyrans linked to piprazine core via …

HF Hammad, AF Darweesh, MA Abdelaziz… - Synthetic …, 2023 - Taylor & Francis
Abstract The precursor, piperazine-1, 4-diylbis (2-oxoethane-2, 1-diyl) bis (4-
formylbenzoate) was prepared by reacting 1, 1'-(piperazine-1, 4-diyl) bis (2-chloroethan-1 …

Two Different Green Catalytic Systems for One‐Pot Regioselective and Chemoselective Synthesis of Some Pyrimido[4,5‐d]Pyrimidinone Derivatives in Water

M Rimaz, J Khalafy, H Mousavi… - Journal of …, 2017 - Wiley Online Library
In this work, we have developed green and efficient regioselective and chemoselective
syntheses of 5‐aryloyl‐1, 3‐dimethyl‐7‐thioxo‐5, 6, 7, 8‐tetrahydropyrimido [4, 5‐d] …

Synthesis of Novel Bis(Sulfanediyl)Bis(Tetrahydropyrimido[4,5-b]Quinoline-4,6-Diones) Linked to Butenyl and Butynyl Spacers via Thioether Linkages

HM Diab, B Elsayed, AF Darweesh… - Polycyclic Aromatic …, 2023 - Taylor & Francis
A synthesis of novel bis (tetrahydropyrimido [4, 5-b] quinoline-4, 6-diones) connected to
butenyl and butynyl spacers via thioether linkages is reported. Two equivalents of the …