Gene therapy is becoming an influential part of the rapidly increasing armamentarium of
biopharmaceuticals for improving health and combating diseases. Currently, three gene …

Neuropsychiatric phenotypes have long been known to be influenced by heritable risk
factors, directly confirmed by the past decade of genetic studies that have revealed specific …

Nonviral gene therapy and DNA vaccines have become the first promising approaches to
treat, cure, or ultimately prevent disease by providing genetic information encoded on a …

The exact mechanisms of nucleic acid (NA) delivery with gene electrotransfer (GET) are still
unknown, which represents a limitation for its broader use. Further, not knowing the effects …

The use of DNA to deliver vaccine antigens offers many advantages, including ease of
manufacture and cost. However, most DNA vaccines are plasmids and must be grown in …

Introducing neural stem/progenitor cells (NS/PCs) for repairing facial nerve injuries could be
an alternative strategy for nerve gap reconstruction. However, the lack of success associated …

Neural stem/progenitor cells (NS/PCs) play a therapeutic role in nervous system diseases
and contribute to functional recovery. However, their efficacy is limited as the majority of cells …

Peripheral artery disease (PAD) is a debilitating and prevalent condition characterized by
blockage of the arteries, leading to limb amputation in more severe cases. Mesenchymal …

Genetically engineered stem cells aid in dissecting basic cell function and are valuable tools
for drug discovery, in vivo cell tracking, and gene therapy. Gene transfer into pluripotent …

Neurotrophic factor genome engineering could have many potential applications not only in
the deeper understanding of neurodegenerative disorders but also in improved …