Calpain signaling: From biology to therapeutic opportunities in neurodegenerative disorders

E Metwally, HA Al-Abbadi, T Hussain… - Frontiers in Veterinary …, 2023 - frontiersin.org
Neurodegenerative disorders represent a major and growing healthcare challenge globally.
Among the numerous molecular pathways implicated in their pathogenesis, calpain …

Genetic and Epigenetic Factors in Gestational Diabetes Mellitus Pathology

Ł Ustianowski, J Udzik, J Szostak, A Gorący… - International Journal of …, 2023 - mdpi.com
Gestational diabetes (GDM) is the carbohydrate intolerance occurring during pregnancy.
The risk factors of GDM include obesity, advanced maternal age, polycystic ovary syndrome …

The effects of sucrose and arsenic on muscular insulin signaling pathways differ between the gastrocnemius and quadriceps muscles

P Pánico, M Velasco, AM Salazar… - Frontiers in …, 2023 - frontiersin.org
Introduction Insulin resistance in muscle can originate from a sedentary lifestyle,
hypercaloric diets, or exposure to endocrine-disrupting pollutants such as arsenic. In …

Genetic variations in IGF2BP2 and CAPN10 and their interaction with environmental factors increase gestational diabetes mellitus risk in Chinese women

R Yang, X Wang, Y Zhang, L Jin, K Zhao, J Chen… - Gene, 2025 - Elsevier
Aim This study aims to investigate the association of the genetic variations in IGF2BP2 and
CAPN10 as well as gene-environment interactions with the risk of gestational diabetes …

[PDF][PDF] Diabetes Mellitus Disclosure: A Comprehensive Review on a Global Issue

R Atique, HA Saeed, A Haidar, A Talib, A Naveed… - researchgate.net
Diabetes mellitus is a long-term metabolic disease associated with increased blood sugar
levels that result from imperfections in insulin secretion. It is a genetic disorder that affects …