Glioblastoma multiforme is the most aggressive malignant tumor of the central nervous
system. Due to the absence of effective pharmacological and surgical treatments, the …

The high incidence of cardiomyopathy in patients with hemosiderosis, particularly in
transfusional iron overload, strongly indicates that iron accumulation in the heart plays a …

Extracellular matrix metalloproteinase inducer (EMMPRIN), known for its ability to induce
matrix metalloproteinase (MMP) expression, was proposed to play a role in the adverse …

Obstructive sleep apnea syndrome (OSAS) is commonly associated with endothelial
dysfunction, atherosclerosis and cardiovascular disorders. On the basis of this observation …

Metalloproteinases (MMPs) have been shown to play a crucial role in synaptic plasticity and
cognitive processes. We recently reported that in the mossy fiber-CA3 hippocampal …

Background In patients with heart failure (HF), circulating neutrophil gelatinase-associated
lipocalin (NGAL) level is increased, which is considered to be a predictor of mortality or renal …

Formation of an abdominal aortic aneurysm is a complex process involving aortic wall
degradation. The matrix metalloproteinases (MMPs) mainly involved in this process are …

心血管疾病的发病率和死亡率逐年上升, 严重危害人类健康. 研究表明中性粒细胞相关脂质运载
蛋白(NGAL), NGAL/基质金属蛋白酶(MMP) 9 复合物参与炎症介质调控及血管重构 …

Chronic pancreatitis (CP) results in impairment of exocrine as well as endocrine functions
and progressive fibrosis. Previous studies, have demonstrated the presence of renin …

摘要目的: 探讨曲美他嗪对慢性心力衰竭患者心功能及MMP-9, TIMP-1 表达的影响. 方法:
选取2012 年3 月至2014 年3 月在我院接受治疗的慢性心力衰竭患者100 例 …