Platelet-to-platelet aggregation is critical to the formation of hemostatic thrombi which limit
bleeding following vascular injury and also contributes to obstructive thrombi in acute …

Integrins are heterodimeric receptors comprising α and β subunits. They are expressed on
the cell surface and play key roles in cell adhesion, migration, and growth. Several types of …

Platelet activation is important for the major role that platelets play in hemostasis and
thrombosis, but it also occurs in a variety of pathologic conditions including acute coronary …

Abstract Itgb3‑integrin‑deficient (Itgb3‑/‑) mice have been reported as a Glanzmann
thrombasthenia (GT) model and have been used for platelet research. However, it remains …

Conventional antiplatelet agents indiscriminately inhibit both thrombosis and hemostasis,
and the increased bleeding risk thus hampers their use at more aggressive dosages to …

Objective: Integrin β3 is implicated in numerous biological processes such as its relevance
to blood triglyceride, yet whether β3 deficiency affects this metabolic process remains …

Potent signaling agents stimulate and guide pulp tissue regeneration, especially in
endodontic treatment of teeth with incomplete root formation. Objective This study evaluated …

Integrins are cellular receptors that regulate cell adhesion and many other cellular functions.
Integrins can be activated via an “inside-out pathway” that is promoted by RAP1 GTPase …