Stem cell–based approaches have received much hype as potential treatments for
neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in …

Stem cells are unique cell populations with the ability to undergo both self-renewal and
differentiation. A wide variety of adult mammalian tissues harbors stem cells, yet “adult” stem …

Human pluripotent stem cells (PSCs) are a promising source of cells for applications in
regenerative medicine. Directed differentiation of PSCs into specialized cells such as spinal …

Parkinson's disease is a widespread condition caused by the loss of midbrain neurons that
synthesize the neurotransmitter dopamine. Cells derived from the fetal midbrain can modify …

We have identified an easily attainable source of primitive, potentially multipotent stem cells
from Wharton's jelly, the matrix of umbilical cord. Wharton's jelly cells have been propagated …

Recent progress shows that neurons suitable for transplantation can be generated from
stem cells in culture, and that the adult brain produces new neurons from its own stem cells …

Injury to a target organ can be sensed by bone marrow stem cells that migrate to the site of
damage, undergo differentiation, and promote structural and functional repair. This …

Although implantation of fetal dopamine (DA) neurons can reduce parkinsonism in patients,
current methods are rudimentary, and a reliable donor cell source is lacking. We show that …

Embryonic stem (ES) cells are clonal cell lines derived from the inner cell mass of the
developing blastocyst that can proliferate extensively in vitro and are capable of adopting all …

Human neurological disorders such as Parkinson's disease, Huntington's disease,
amyotrophic lateral sclerosis (ALS), Alzheimer's disease, multiple sclerosis (MS), stroke, and …