Calcium phosphates (CaPs) are the most widely used bone substitutes in bone tissue
engineering due to their compositional similarities to bone mineral and excellent …

Effective treatment of critical-size defects is a key challenge in restorative surgery of bone.
The strategy covers the implantation of biocompatible, osteoconductive, bioactive and …

There is a pressing need for long-term, controlled drug release for sustained treatment of
chronic or persistent medical conditions and diseases. Guided drug delivery is difficult …

Synthetic hydroxyapatite plays a key role in implantology, stomatology, and regenerative
medicine. Thanks to its non-toxicity and biocompatibility with bone and mineralised dental …

Chronic osteomyelitis is a major challenge in bone surgery. Conventional use of antibiotics
is not an effective way to control the malaise due to so many reasons. Determination of …

The state-of-the-art on calcium orthophosphate (CaPO4)-containing biocomposites and
hybrid biomaterials suitable for biomedical applications is presented. Since these types of …

The state-of-the-art of biocomposites and hybrid biomaterials based on calcium
orthophosphates that are suitable for biomedical applications is presented in this review …

Disadvantages of conventional drug delivery systems (DDS), such as systemic circulation,
interaction with physiochemical factors, reduced bioavailability, and insufficient drug …

Due to a great chemical similarity with the biological calcified tissues, many calcium
orthophosphates possess remarkable biocompatibility and bioactivity. Materials scientists …

Drug delivery is known as an approach for transporting a pharmaceutical compound in
animals and the human body to achieve effective therapy. Drug carriers are usually based …