Migraine is a highly prevalent neurovascular disorder that can be provoked by infusion of
calcitonin gene-related peptide (CGRP). CGRP, a neuropeptide released from activated …

Although family BG protein-coupled receptors (GPCRs) contain only 15 members, they play
key roles in transmembrane signal transduction of hormones. Family B GPCRs are drug …

The cellular and molecular mechanisms mediating histamine-independent itch in primary
sensory neurons are largely unknown. Itch induced by chloroquine (CQ) is a common side …

Calcitonin gene‐related peptide (CGRP) is a key mediator in primary headaches including
migraine. Animal models of meningeal nociception demonstrate both peripheral and central …

Based on preclinical and clinical studies, the neuropeptide calcitonin gene-related peptide
(CGRP) is proposed to play a central role in the underlying pathology of migraine. CGRP …

Secretin family G protein-coupled receptors (GPCRs) are important therapeutic targets for
migraine, diabetes, bone disorders, inflammatory disorders and cardiovascular disease …

The calcitonin receptor (CTR) and calcitonin receptor‐like receptor (CLR) are two of the 15
human family B (or Secretin‐like) GPCRs. CTR and CLR are of considerable biological …

Calcitonin gene-related peptide (CGRP) is a promiscuous peptide, similar to many other
members of the calcitonin family of peptides. The potential of CGRP to act on many different …

The mechanisms responsible for the phenomenon of an accelerated speed of fracture
healing in patients with traumatic brain injury (TBI) remain unclear. The present study was …

The neuropeptide calcitonin gene‐related peptide (CGRP) is implicated in the underlying
pathology of migraine. Serum levels of CGRP, which are elevated during a migraine attack …