The nervous system is populated by numerous types of neurons, each bearing a dendritic
arbor with a characteristic morphology. These type-specific features influence many aspects …

Protein SUMOylation is a critically important posttranslational protein modification that
participates in nearly all aspects of cellular physiology. In the nearly 20 years since its …

Nervous systems contain sensory neurons, local neurons, projection neurons, and motor
neurons. To understand how these building blocks form whole circuits, we must distil these …

The definition of neuronal type and how it relates to the transcriptome are open questions.
Drosophila olfactory projection neurons (PNs) are among the best-characterized neuronal …

Neurotransmitters are released at presynaptic active zones (AZs). In the fly Drosophila,
monoclonal antibody (MAB) nc82 specifically labels AZs. We employ nc82 to identify …

Neural circuit mapping is generating datasets of tens of thousands of labeled neurons. New
computational tools are needed to search and organize these data. We present NBLAST, a …

Neuron-glia communication is central to all nervous system responses to trauma, yet neural
injury signaling pathways remain poorly understood. Here we explore cellular and …

Local interneurons are essential in information processing by neural circuits. Here we
present a comprehensive genetic, anatomical and electrophysiological analysis of local …

Molecular interactions at the cellular interface mediate organized assembly of single cells
into tissues and, thus, govern the development and physiology of multicellular organisms …

Courtship is an innate sexually dimorphic behaviour that can be observed in naive animals
without previous learning or experience, suggesting that the neural circuits that mediate this …