Visible-to-NIR-light activated release: from small molecules to nanomaterials
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …
Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …
over 50 years and leading to significant biotechnological advancements in drug delivery …
Remote light‐responsive nanocarriers for controlled drug delivery: advances and perspectives
Engineering of smart photoactivated nanomaterials for targeted drug delivery systems (DDS)
has recently attracted considerable research interest as light enables precise and accurate …
has recently attracted considerable research interest as light enables precise and accurate …
Stimulus-cleavable chemistry in the field of controlled drug delivery
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …
owing to their capability of achieving exquisite control over drug release via the exposure to …
Self‐immolative spacers: kinetic aspects, structure–property relationships, and applications
A Alouane, R Labruère, T Le Saux… - Angewandte Chemie …, 2015 - Wiley Online Library
Self‐immolative spacers are covalent assemblies tailored to correlate the cleavage of two
chemical bonds after activation of a protective part in a precursor: Upon stimulation, the …
chemical bonds after activation of a protective part in a precursor: Upon stimulation, the …
[HTML][HTML] Recent advances in self-immolative linkers and their applications in polymeric reporting systems
AG Gavriel, MR Sambrook, AT Russell, W Hayes - Polymer Chemistry, 2022 - pubs.rsc.org
Interest in self-immolative chemistry has grown over the past decade with more research
groups harnessing the versatility to control the release of a compound from a larger …
groups harnessing the versatility to control the release of a compound from a larger …
Triggering depolymerization: progress and opportunities for self-immolative polymers
Polymers that depolymerize end-to-end upon cleavage of their backbones or end-caps,
often termed “self-immolative” polymers (SIPs), have garnered significant interest in recent …
often termed “self-immolative” polymers (SIPs), have garnered significant interest in recent …
Dendritic, oligomeric, and polymeric self-immolative molecular amplification
The development of new chemical tools for the purpose of molecular amplification is
arguably one of the most central challenges in science. Such tools have traditionally been …
arguably one of the most central challenges in science. Such tools have traditionally been …
Self-immolative polymersomes for high-efficiency triggered release and programmed enzymatic reactions
Stimuli-triggered disassembly of block copolymer vesicles or polymersomes has been
conventionally achieved via solubility switching of the bilayer-forming block, requiring …
conventionally achieved via solubility switching of the bilayer-forming block, requiring …
Controlled depolymerization: stimuli-responsive self-immolative polymers
Self-immolative polymers (SIPs) are unique macromolecules that are able to react to
multiple types of environmental influences by giving amplified response outputs. When …
multiple types of environmental influences by giving amplified response outputs. When …