Estrogen receptors alpha (ERα) and beta (ERβ) are nuclear transcription factors that are
involved in the regulation of many complex physiological processes in humans. Modulation …

The incidence of many types of cancer arising in organs with non-reproductive functions is
significantly higher in male populations than in female populations, with associated …

Estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) belong to a superfamily of
nuclear receptors called steroid hormone receptors, which, upon binding ligand, dimerize …

Nonalcoholic fatty liver disease (NAFLD) caused by fat accumulation in the liver is globally
the most common cause of chronic liver disease. Simple steatosis can progress to …

Simple Summary Kidney cancer is a frequent malignant tumor that accounts for
approximately 5% of all cancer incidences. It affects both males and females, but males are …

Estrogen Receptor-β (ERβ) has been implicated in many cancers. In prostate and breast
cancer its function is controversial, but genetic studies implicate a role in cancer …

Recent studies indicated that the estrogen receptor beta (ERβ) could affect the progression
of prostate and bladder tumors, however, its roles in the renal cell carcinoma (RCC), remain …

A gender discrepancy exists in the incidence of both urothelial and kidney carcinomas, with
more men presenting with these cancers than women. Men have a threefold greater risk of …

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. The
incidence of HCC is strikingly higher in males than in females. The remarkable gender …

Men are more frequently diagnosed with kidney cancer than women, with a more aggressive
histology, larger tumors, a higher grade and stage, and worse oncological outcomes …